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未识别的膀胱嗜铬细胞瘤引发高血压危象。

Unrecognised paraganglioma of the urinary bladder precipitating hypertensive crisis.

机构信息

Urological Surgery, Barwon Health, Geelong, Victoria, Australia

Urological Surgery, Barwon Health, Geelong, Victoria, Australia.

出版信息

BMJ Case Rep. 2024 Apr 29;17(4):e259283. doi: 10.1136/bcr-2023-259283.

Abstract

Bladder paragangliomas (bPGLs) account for only 0.06% of all bladder tumours, most commonly presenting with post-micturition syncope and hypertensive crisis. Silent paragangliomas are very rare, and failure to recognise them in the perioperative setting can precipitate a hypertensive crisis in the absence of sufficient alpha-blockade. Here, we describe a case of unrecognised bPGL in a woman with pre-existing hypertension and a single prior episode of haematuria thought to be related to urothelial carcinoma. She was found to have a low-grade non-invasive papillary urothelial carcinoma (potentially the cause of her haematuria) and an unrelated vascular-appearing tumour causing hypertensive crisis and broad complex tachycardia on resection. This was confirmed to be a bPGL on histology for which she underwent definitive management with a partial cystectomy following blood pressure management.

摘要

膀胱副神经节瘤(bPGL)占所有膀胱肿瘤的 0.06%,最常见的表现为排尿后晕厥和高血压危象。无症状的副神经节瘤非常罕见,如果在围手术期未能识别它们,在没有足够的α受体阻滞剂的情况下,可能会引发高血压危象。在这里,我们描述了一例患有高血压的女性中未被识别的 bPGL,她曾有过一次血尿病史,既往认为与尿路上皮癌有关。她被发现患有低度非浸润性乳头状尿路上皮癌(可能是血尿的原因)和一个无关的血管样肿瘤,导致高血压危象和广泛复杂的心动过速,在切除后。组织学证实为 bPGL,她在血压管理后接受了部分膀胱切除术的确定性治疗。

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