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预测远外侧腰椎间盘切除术患者的预后。

Predicting patient outcomes after far lateral lumbar discectomy.

机构信息

Department of Neurosurgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.

McKenna EpiLog Fellowship in Population Health, at the University of Pennsylvania, Philadelphia, PA, USA.

出版信息

Clin Neurol Neurosurg. 2021 Apr;203:106583. doi: 10.1016/j.clineuro.2021.106583. Epub 2021 Mar 3.

Abstract

INTRODUCTION

The LACE+ (Length of Stay, Acuity of Admission, Charlson Comorbidity Index (CCI) Score, Emergency Department (ED) visits within the previous 6 months) index has never been tested in a purely spine surgery population. This study assesses the ability of LACE + to predict adverse patient outcomes following discectomy for far lateral disc herniation (FLDH).

PATIENTS AND METHODS

Data were obtained for patients (n = 144) who underwent far lateral lumbar discectomy at a single, multi-hospital academic medical center (2013-2020). LACE + scores were calculated for all patients with complete information (n = 100). The influence of confounding variables was assessed and controlled with stepwise regression. Logistic regression was used to test the ability of LACE + to predict risk of unplanned hospital readmission, ED visits, outpatient office visits, and reoperation after surgery.

RESULTS

Mean age of the population was 61.72 ± 11.55 years, 69 (47.9 %) were female, and 126 (87.5 %) were non-Hispanic white. Patients underwent either open (n = 92) or endoscopic (n = 52) surgery. Each point increase in LACE + score significantly predicted, in the 30-day (30D) and 30-90-day (30-90D) post-discharge window, higher risk of readmission (p = 0.005, p = 0.009; respectively) and ED visits (p = 0.045). Increasing LACE + also predicted, in the 30D and 90-day (90D) post-discharge window, risk of reoperation (p = 0.022, p = 0.016; respectively), and repeat neurosurgical intervention (p = 0.026, p = 0.026; respectively). Increasing LACE + score also predicted risk of reoperation (p = 0.011) within 30 days of initial surgery.

CONCLUSIONS

LACE + may be suitable for characterizing risk of adverse perioperative events for patients undergoing far lateral discectomy.

摘要

简介

LACE+(住院时间、入院时的病情严重程度、Charlson 合并症指数(CCI)评分、前 6 个月内急诊就诊次数)指数从未在单纯的脊柱手术人群中进行过测试。本研究评估了 LACE+在预测极外侧椎间盘突出症(FLDH)患者椎间盘切除术后不良患者结局方面的能力。

患者和方法

从一家多医院学术医疗中心(2013-2020 年)获得了 144 例接受极外侧腰椎间盘切除术的患者的数据。对所有信息完整的患者(n=100)计算了 LACE+评分。通过逐步回归评估并控制混杂变量的影响。使用逻辑回归测试 LACE+预测手术 30 天内、30-90 天内非计划性住院再入院、急诊就诊、门诊就诊和再次手术的风险的能力。

结果

人群的平均年龄为 61.72±11.55 岁,69 例(47.9%)为女性,126 例(87.5%)为非西班牙裔白人。患者接受了开放手术(n=92)或内镜手术(n=52)。LACE+评分每增加 1 分,在术后 30 天(30D)和 30-90 天(30-90D)的出院后窗口内,再入院(p=0.005,p=0.009)和急诊就诊(p=0.045)的风险显著增加。LACE+评分的增加还预测了术后 30 天(30D)和 90 天(90D)的再手术(p=0.022,p=0.016)和重复神经外科干预(p=0.026,p=0.026)的风险。LACE+评分的增加还预测了初次手术后 30 天内再手术(p=0.011)的风险。

结论

LACE+可能适合描述接受极外侧椎间盘切除术的患者围手术期不良事件的风险。

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