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通过巴基斯坦成年人人体测量指数预测 2 型糖尿病风险——对 2016-2017 年巴基斯坦第二次国家糖尿病调查(NDSP-07)的子分析。

Predicting the risk of type 2 diabetes through anthropometric indices in Pakistani adults- A sub-analysis of second National diabetes survey of Pakistan 2016-2017 (NDSP-07).

机构信息

Department of Medicine, Baqai Institute of Diabetology and Endocrinology, Baqai Medical University, Karachi, Pakistan.

Department of Research, Baqai Institute of Diabetology and Endocrinology, Baqai Medical University, Karachi, Pakistan.

出版信息

Diabetes Metab Syndr. 2021 Mar-Apr;15(2):543-547. doi: 10.1016/j.dsx.2021.02.030. Epub 2021 Feb 27.

Abstract

BACKGROUND AND AIM

Excess adiposity is associated with an increased risk of diabetes. Amongst the various measures of adiposity, the most appropriate one to predict the risk of diabetes remains debatable. Therefore, the aim of this study was to compare the ability of body mass index (BMI), waist circumference (WC), and waist-to-hip ratio (WHR) in predicting type 2 diabetes mellitus (DM) among Pakistani adults.

SUBJECTS AND METHODS

This was the sub-analysis of a large population based Second National Diabetes Survey of Pakistan (NDSP) 2016-2017. With this survey, 10834 individuals were recruited and 4788 individuals fulfilled the inclusion criteria for this sub-analysis (subjects with missing anthropometric details were excluded). Participants were categorized into two groups; subjects with type 2 DM and subjects without DM. Data of participants was collected via pre-designed detailed questionnaire. Clinical and anthropometric measurements were measured using standardized techniques.

RESULTS

Out of 4788 individuals, 3085(64.4%) were non-DM subjects and 1703(35.6%) were type 2 DM subjects with mean age of 39.78 ± 13.79 and 50.38 ± 11.33 years, respectively. Logistic regression analysis revealed a significant association of WC with type 2 diabetes after adjustment for possible confounders. Area under the curve (AUC) of WC was found higher than AUC of BMI and WHR.

CONCLUSION

The findings from second NDSP (2016-2017) demonstrated that WC is a better marker than WHR and BMI in predicting type 2 DM for Pakistani population.

摘要

背景与目的

肥胖与糖尿病风险增加相关。在各种肥胖测量指标中,预测糖尿病风险最合适的指标仍存在争议。因此,本研究旨在比较体质指数(BMI)、腰围(WC)和腰臀比(WHR)在预测巴基斯坦成年人 2 型糖尿病(DM)中的作用。

受试者和方法

这是巴基斯坦第二次全国糖尿病调查(NDSP)2016-2017 的子分析。通过这项调查,共招募了 10834 人,其中 4788 人符合本亚分析的纳入标准(排除了缺少人体测量学细节的受试者)。将受试者分为两组:2 型 DM 组和非 DM 组。通过预先设计的详细问卷收集参与者的数据。使用标准化技术测量临床和人体测量学指标。

结果

在 4788 名受试者中,3085 名(64.4%)是非 DM 受试者,1703 名(35.6%)是 2 型 DM 受试者,平均年龄分别为 39.78±13.79 岁和 50.38±11.33 岁。经过可能的混杂因素调整后,逻辑回归分析显示 WC 与 2 型糖尿病显著相关。WC 的曲线下面积(AUC)高于 BMI 和 WHR 的 AUC。

结论

第二次 NDSP(2016-2017 年)的结果表明,在预测巴基斯坦人群 2 型 DM 方面,WC 是比 WHR 和 BMI 更好的标志物。

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