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孟加拉国人口肥胖和 2 型糖尿病的人体测量学指标:昌德拉农村糖尿病研究(CRDS)。

Anthropometric indices of obesity and type 2 diabetes in Bangladeshi population: Chandra Rural Diabetes Study (CRDS).

出版信息

Obes Res Clin Pract. 2014 May-Jun;8(3):e201-98. doi: 10.1016/j.orcp.2013.06.001.

DOI:10.1016/j.orcp.2013.06.001
PMID:24847663
Abstract

BACKGROUND

Obesity is a risk factor for type 2 diabetes (DM); however, no study has specially assessed the anthropometric indices as predictors of diabetes in rural Bangladeshi population.

OBJECTIVE

To identify markers for diabetes through body mass index (BMI), waist circumference (WC), waist hip ratio (WHR) and waist height ratio (WHtR) and identify the optimal cut-off values suitable for Bangladeshi adult population.

METHODS

A total of 2293 subjects aged ≥20 years from rural Bangladesh were randomly recruited to participate in a population-based, cross sectional survey. Age adjusted data for anthropometric indices and diabetes risk were assessed and their relationships were examined.

RESULTS

Age adjusted prevalence of DM in men and women were 9.5% and 7.0%, respectively. Both men and women with DM had a higher rate of general obesity (defined by BMI) and central obesity (defined by WC, WHR and WHtR) than non-diabetic subjects. In both men and women the most sensitive indice was WHR for predicting DM. The appropriate cut-offs values for WHR to predict DM in men and women were 0.93 and 0.87, respectively. WC of 82 cm for both sexes was appropriate to predict DM. Those of BMI and WHtR were 21.2 kg/m2, 21.8 kg/m2 and 0.53, 0.54 in men and women, respectively.

CONCLUSIONS

Compared with BMI, measures of central obesity, WHR, WC, WHtR showed a better association with the risk of DM for both sexes in rural Bangladeshi population. Follow-up studies are needed for validifying these cut-offs values.

摘要

背景

肥胖是 2 型糖尿病(DM)的一个危险因素;然而,尚无研究专门评估身体质量指数(BMI)、腰围(WC)、腰臀比(WHR)和腰高比(WHtR)等人体测量指标作为孟加拉农村人群糖尿病的预测指标。

目的

通过 BMI、WC、WHR 和 WHtR 确定糖尿病的标志物,并确定适合孟加拉成年人群的最佳截断值。

方法

共招募了 2293 名年龄≥20 岁的孟加拉农村居民参加一项基于人群的横断面调查。评估了年龄校正后的人体测量指标和糖尿病风险数据,并研究了它们之间的关系。

结果

男性和女性的年龄校正后糖尿病患病率分别为 9.5%和 7.0%。患有糖尿病的男性和女性的一般肥胖(由 BMI 定义)和中心性肥胖(由 WC、WHR 和 WHtR 定义)的发生率均高于非糖尿病患者。在男性和女性中,WHR 是预测 DM 最敏感的指标。男性和女性预测 DM 的最佳 WHR 截断值分别为 0.93 和 0.87。WC 对于男女预测 DM 均为 82cm 是合适的。对于 BMI 和 WHtR,男女的合适截断值分别为 21.2kg/m2、21.8kg/m2、0.53、0.54。

结论

与 BMI 相比,中心性肥胖指标、WHR、WC、WHtR 与孟加拉农村人群两性患 DM 的风险相关性更好。需要进一步的随访研究来验证这些截断值。

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