Acta Chir Plast. 2020 Winter;62(3-4):103-110.
The field of tissue engineering applies principles of engineering and life sciences for the development of functional biologic substitutes. The increasing need of tissue for challenging reconstructive surgeries places plastic surgeons involvement as vital in the research and development of engineered constructs and subsequent use. This narrative review aims to summarize tissue engineering principles, to update on its current uses and breakthroughs, to approach its current limitations and possible future directions for this exciting new field of medicine. This revision addressed tissue engineering utilisation in skin lesions, craniocervical defects, musculoskeletal defects, peripheral nerves lesions, vascular tissue defects and adipose tissue uses. Research in tissue engineering is increasing exponentially, however, and although there are already several engineered constructs available, its widespread clinical application is still a hope. More long-term studies that answer outstanding issues are needed in order for that to become reality.
组织工程学将工程学和生命科学的原理应用于功能性生物替代品的开发。由于复杂重建手术对组织的需求不断增加，整形外科医生在工程构建体的研究和开发以及随后的应用中发挥着至关重要的作用。本叙述性综述旨在总结组织工程学原理，更新其当前用途和突破，探讨其当前的局限性以及这个令人兴奋的医学新领域的未来方向。本修订涉及组织工程学在皮肤损伤、颅颈缺损、肌肉骨骼缺损、周围神经损伤、血管组织缺损和脂肪组织中的应用。组织工程学的研究正在呈指数级增长，然而，尽管已经有几种工程构建体可用，但它的广泛临床应用仍然是一个希望。需要进行更多的长期研究来回答悬而未决的问题，以便使其成为现实。
