Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100191, China.
Biomed Environ Sci. 2021 Feb 20;34(2):163-169. doi: 10.3967/bes2021.022.
This study aims to investigate the correlation of an ultrasonic scoring system with intraoperative blood loss (IBL) in placenta accreta spectrum (PAS) disorders.
A retrospective cohort study was conducted between January 2015 and November 2019. Clinical data for patients with PAS have been obtained from medical records. Generalized additive models were used to explore the nonlinear relationships between ultrasonic scores and IBL. Logistic regressions were used to determine the differences in the risk of IBL ≥ 1,500 mL among groups with different ultrasonic scores.
A total of 332 patients participated in the analysis. Generalized additive models showed a significant positive correlation between score and blood loss. The amount of IBL was increased due to the rise in the ultrasonic score. All cases were divided into three groups according to the scores (low score group: ≤ 6 points, = 147; median score group: 7-9 points, = 126; and high score group: ≥ 10 points, = 59). Compared with the low score group, the high score group showed a higher risk of IBL ≥ 1,500 mL [odds ratio, 15.09; 95% confidence interval (3.85, 59.19); ≤ 0.001] after a multivariable adjustment.
The risk of blood loss equal to or greater than 1,500 mL increases further when ultrasonic score greater than or equal to 10 points, the preparation for transfusion and referral mechanism should be considered.
本研究旨在探讨超声评分系统与胎盘植入谱系(PAS)疾病术中出血量(IBL)的相关性。
回顾性队列研究于 2015 年 1 月至 2019 年 11 月进行。从病历中获取 PAS 患者的临床数据。广义加性模型用于探索超声评分与 IBL 之间的非线性关系。逻辑回归用于确定不同超声评分组之间 IBL≥1500ml 的风险差异。
共有 332 例患者参与分析。广义加性模型显示评分与出血量之间存在显著正相关。超声评分升高导致 IBL 量增加。根据评分将所有病例分为三组(低评分组:≤6 分,n=147;中评分组:7-9 分,n=126;高评分组:≥10 分,n=59)。与低评分组相比,多变量调整后高评分组 IBL≥1500ml 的风险更高[比值比,15.09;95%置信区间(3.85,59.19);P≤0.001]。
当超声评分大于等于 10 分时,出血量等于或大于 1500ml 的风险进一步增加,应考虑输血和转诊机制的准备。