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扩张性右心室的右心室血流动力学:基于血斑追踪超声心动图的能量损失估计-儿童初步研究。

Right Ventricular Flow Dynamics in Dilated Right Ventricles: Energy Loss Estimation Based on Blood Speckle Tracking Echocardiography-A Pilot Study in Children.

机构信息

The Hospital for Sick Children, Toronto, Ontario, Canada; Department of Circulation and Medical Imaging, Norwegian University of Science and Technology (NTNU), Trondheim, Norway; Department of Paediatrics, Montreal Children's Hospital, McGill University Health Centre, Montreal, Quebec, Canada.

Department of Circulation and Medical Imaging, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.

出版信息

Ultrasound Med Biol. 2021 Jun;47(6):1514-1527. doi: 10.1016/j.ultrasmedbio.2021.02.004. Epub 2021 Mar 6.

DOI:10.1016/j.ultrasmedbio.2021.02.004
PMID:33685744
Abstract

Using blood speckle tracking (BST) based on high-frame-rate echocardiography (HFRE), we compared right ventricle (RV) flow dynamics in children with atrial septal defects (ASDs) and repaired tetralogy of Fallot (rTOF). Fifty-seven children with rTOF with severe pulmonary insufficiency (PI) (n = 21), large ASDs (n = 11) and healthy controls (CTL, n = 25) were included. Using a flow phantom, we studied the effects of imaging plane and smoothing parameters on 2-D energy loss (EL). RV diastolic EL was similar in ASD and rTOF, but both were greater than in CTL. Locations of high EL were similar in all groups in systole, occurring in the RV outflow tract and around the tricuspid valve leaflets in early diastole. An additional apical early diastolic area of EL was noted in rTOF, corresponding to colliding tricuspid inflow and PI. The flow phantom revealed that EL varied with imaging plane and smoothing settings but that the EL trend was preserved if kept consistent.

摘要

我们使用基于高帧率超声心动图(HFRE)的血斑跟踪(BST)技术,比较了房间隔缺损(ASD)和修复性法洛四联症(rTOF)患儿的右心室(RV)流动力学。共纳入了 57 例伴有严重肺功能不全(PI)的 rTOF 患儿(n=21)、大型 ASD(n=11)和健康对照组(CTL,n=25)。我们使用流量模型研究了成像平面和平滑参数对二维能量损耗(EL)的影响。ASD 和 rTOF 的 RV 舒张期 EL 相似,但均大于 CTL。在收缩期,各组的高 EL 位置相似,均发生在 RV 流出道和三尖瓣瓣叶周围的早期舒张期。在 rTOF 中还观察到心尖早期舒张期的额外 EL 区域,与三尖瓣流入和 PI 碰撞有关。流量模型显示 EL 随成像平面和平滑设置而变化,但如果保持一致,EL 趋势得以保留。

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