Department of Preventive Medicine and Public Health, University of Navarra, Pamplona, Spain.
IdiSNA, Instituto de Investigación Sanitaria de Navarra, Pamplona, Spain.
Sci Rep. 2021 Mar 8;11(1):5431. doi: 10.1038/s41598-021-84839-w.
Retention is a key element in HIV prevention programs. In Sub-Saharan Africa most data on retention come from HIV clinical trials or people living with HIV attending HIV treatment and control programs. Data from observational cohorts are less frequent. Retention at 6-/12-month follow-up and its predictors were analyzed in OKAPI prospective cohort. From April 2016 to April 2018, 797 participants aged 15-59 years attending HIV Voluntary Counseling and Testing in Kinshasa were interviewed about HIV-related knowledge and behaviors at baseline and at 6- and 12-month follow-ups. Retention rates were 57% and 27% at 6- and 12-month follow up; 22% of participants attended both visits. Retention at 6-month was significantly associated with 12-month retention. Retention was associated with low economic status, being studying, daily/weekly Internet access, previous HIV tests and aiming to share HIV test with partner. Contrarily, perceiving a good health, living far from an antiretroviral center, daily/weekly alcohol consumption and perceiving frequent HIV information were inversely associated with retention. In conclusion, a high attrition was found among people attending HIV testing participating in a prospective cohort in Kinshasa. Considering the low retention rates and the predictors found in this study, more HIV cohort studies in Kinshasa need to be evaluated to identify local factors and strategies that could improve retention if needed.
保留率是艾滋病毒预防规划的关键要素。在撒哈拉以南非洲,大多数保留率数据来自艾滋病毒临床试验或接受艾滋病毒治疗和控制方案的艾滋病毒感染者。观察性队列的数据则较为少见。本研究对 OKAPI 前瞻性队列中 6 个月和 12 个月的随访保留率及其预测因素进行了分析。2016 年 4 月至 2018 年 4 月,在金沙萨参加艾滋病毒自愿咨询和检测的 797 名年龄在 15-59 岁的参与者在基线和 6 个月及 12 个月随访时接受了艾滋病毒相关知识和行为访谈。6 个月和 12 个月随访的保留率分别为 57%和 27%;22%的参与者参加了两次随访。6 个月的保留率与 12 个月的保留率显著相关。保留率与经济状况较差、正在学习、每天/每周上网、以前进行过艾滋病毒检测以及打算与伴侣分享艾滋病毒检测结果有关。相反,认为自己健康状况良好、远离抗逆转录病毒中心、每天/每周饮酒以及认为经常收到艾滋病毒信息与保留率呈负相关。总之,在金沙萨参加艾滋病毒检测并参与前瞻性队列的人群中发现了较高的流失率。考虑到本研究中发现的低保留率和预测因素,需要对金沙萨更多的艾滋病毒队列研究进行评估,以确定当地的因素和策略,如有必要,以提高保留率。