Department of Anatomy and Physiology, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Melbourne, VIC, Australia.
J Neuroendocrinol. 2021 Apr;33(4):e12947. doi: 10.1111/jne.12947. Epub 2021 Mar 9.
Insulin signals to the brain where it coordinates multiple physiological processes underlying energy and glucose homeostasis. This review explores where and how insulin interacts within the brain parenchyma, how brain insulin signalling functions to coordinate energy and glucose homeostasis and how this contributes to the pathogenesis of metabolic disease.
胰岛素向大脑发出信号，协调能量和葡萄糖稳态的多个生理过程。本文探讨了胰岛素在脑实质中的相互作用位置和方式、大脑胰岛素信号如何协调能量和葡萄糖稳态以及这如何促进代谢疾病的发病机制。
