Roberts S R, Esther J W, Brewer J H
Department of Surgery, St. Luke's Hospital, Kansas City, MO 64111.
South Med J. 1988 May;81(5):675-6. doi: 10.1097/00007611-198805000-00036.
The patient described was immunologically compromised by multisystem trauma. Pasteurella multocida was isolated from the respiratory tract and subsequently from the cerebrospinal fluid; direct spread apparently occurred by way of a basilar skull fracture. Sepsis was absent. He was successfully treated but subsequently had hydrocephalus, which has not previously been reported to occur after P multocida meningitis. Because of the opportunistic nature of this infrequent human commensal and the significant morbidity and mortality associated with it, we believe that isolation of Pasteurella multocida from the respiratory tract justifies treatment, especially in the compromised host.
该患者因多系统创伤导致免疫功能受损。从呼吸道分离出多杀巴斯德菌,随后又从脑脊液中分离出该菌;显然是通过颅底骨折发生了直接传播。未发生脓毒症。他得到了成功治疗,但随后出现了脑积水,此前尚未有关于多杀巴斯德菌脑膜炎后发生脑积水的报道。由于这种罕见的人体共生菌具有机会致病性及其相关的显著发病率和死亡率,我们认为从呼吸道分离出多杀巴斯德菌就有理由进行治疗,尤其是在免疫功能受损的宿主中。