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Understanding Barriers to Hepatitis C Antiviral Treatment in Low-Middle-Income Countries.了解低收入和中等收入国家丙型肝炎抗病毒治疗的障碍
Healthcare (Basel). 2024 Dec 30;13(1):43. doi: 10.3390/healthcare13010043.
5
Widespread hepatitis C virus transmission network among people who inject drugs in Kenya.肯尼亚注射吸毒者中广泛存在的丙型肝炎病毒传播网络。
Int J Infect Dis. 2024 Oct;147:107215. doi: 10.1016/j.ijid.2024.107215. Epub 2024 Sep 7.
6
Predictors of hepatitis C cure among people who inject drugs treated with directly observed therapy supported by peer case managers in Kenya.肯尼亚接受同伴个案管理员支持的直接观察治疗的注射吸毒者中丙型肝炎治愈的预测因素。
Int J Drug Policy. 2023 Mar;113:103959. doi: 10.1016/j.drugpo.2023.103959. Epub 2023 Feb 7.
7
Challenges and best practices for hepatitis C care among people who inject drugs in resource limited settings: focus group discussions with healthcare providers in Kenya.资源有限环境下,针对注射吸毒人群的丙型肝炎治疗的挑战与最佳实践:肯尼亚医护人员的焦点小组讨论。
Glob Public Health. 2022 Dec;17(12):3627-3637. doi: 10.1080/17441692.2022.2110919. Epub 2022 Aug 8.
8
Barriers and facilitators of HIV and hepatitis C care among people who inject drugs in Nairobi, Kenya: a qualitative study with peer educators.肯尼亚内罗毕注射吸毒者中艾滋病毒和丙型肝炎护理的障碍和促进因素:同伴教育者的定性研究。
Harm Reduct J. 2021 Dec 18;18(1):133. doi: 10.1186/s12954-021-00580-7.

肯尼亚注射吸毒人群中丙型肝炎相关知识、态度和感知风险行为:一项定性研究。

Hepatitis C-related knowledge, attitudes and perceived risk behaviours among people who inject drugs in Kenya: A qualitative study.

机构信息

Department of Medicine, Albert Einstein College of Medicine / Montefiore Medical Center, Bronx, NY, USA.

Yale University, Yale School of Nursing, Orange, CT, USA.

出版信息

Glob Public Health. 2022 Jun;17(6):1016-1028. doi: 10.1080/17441692.2021.1896763. Epub 2021 Mar 9.

DOI:10.1080/17441692.2021.1896763
PMID:33689563
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8426429/
Abstract

Despite disproportionately high rates of Hepatitis C (HCV) among people who inject drugs (PWID) in low- and middle-income countries (LMICs), understanding of HCV-related knowledge, attitudes and perceived risk behaviours among this population remains limited. We aimed to elucidate knowledge, attitudes and experiences that could minimise transmission risk and maximise HCV treatment engagement among PWID in Kenya following the integration of HCV screening and education with needle and syringe programmes in drop-in-centres (DICs). We recruited 40 PWID with chronic HCV attending DICs in Nairobi and Coastal Kenya. Semi-structured interviews revealed a general understanding of HCV and awareness of HCV risk behaviours among participants; however, many felt limited control over their transmission risk due to factors such as 'local doctors', or individuals who perform a high volume of high-risk injections. Financial barriers, distance to clinic, poor health status and HCV-related stigma were all noted as barriers to HCV treatment. In conclusion, basic knowledge of and motivation for HCV treatment among PWID accessing DICs in Kenya was high; however, structural barriers and stigma complicate access to care. Local education programmes can address knowledge gaps, and behavioural and structural interventions can maximise the impact of HCV care in LMICs.

摘要

尽管在低收入和中等收入国家(LMICs)中,注射毒品者(PWID)中丙型肝炎(HCV)的发病率极高,但对于该人群中与 HCV 相关的知识、态度和感知风险行为的了解仍然有限。我们旨在阐明肯尼亚在 DIC 中整合 HCV 筛查和教育与针具交换计划后,能够最大限度地减少 PWID 传播风险并最大程度地提高 HCV 治疗参与率的知识、态度和经验。我们在肯尼亚内罗毕和沿海地区的 DIC 招募了 40 名患有慢性 HCV 的 PWID。半结构化访谈揭示了参与者对 HCV 的一般认识和对 HCV 风险行为的认识;然而,许多人由于“当地医生”或进行大量高风险注射的个人等因素,感到对自己的传播风险控制有限。经济障碍、距离诊所远、健康状况不佳和与 HCV 相关的耻辱感均被认为是 HCV 治疗的障碍。总之,肯尼亚 DIC 中接受治疗的 PWID 对 HCV 治疗的基本知识和动机很高;但是,结构性障碍和耻辱感使获得护理变得复杂。当地教育计划可以解决知识差距,行为和结构性干预措施可以最大程度地提高 HCV 在 LMICs 中的治疗效果。