Adult Congenital Heart Disease Unit, Monaldi Hospital, Naples, Italy.
Adult Congenital Heart Disease Unit, Monaldi Hospital, Naples, Italy; Paediatric Cardiology Unit, "L.Vanvitelli" University - Monaldi Hospital, Naples, Italy.
J Electrocardiol. 2021 May-Jun;66:16-17. doi: 10.1016/j.jelectrocard.2020.07.012. Epub 2020 Jul 30.
A 3-months-old infant was urgently admitted for drowsiness and lack of appetite started 24 h before. The ECG showed sinus rhythm with a prolonged AV interval (200 ms) and very large QRS complexes (280 ms) due to Flecainide overdosing following incorrectly administration for poor communication between parents resulted in both giving a dose to the infant. Flecainide serum level was 1.2μg/ml, confirming the diagnosis of an accidental drug intoxication. The patient started continue hydration with a close monitoring. Three hours later a significant narrowing of the QRS complex (150 ms) was observed, then over the following 24 h, the QRS almost completely normalized.
一名 3 个月大的婴儿因嗜睡和食欲不振紧急入院，这些症状在 24 小时前开始出现。心电图显示窦性节律，AV 间期延长（200ms），QRS 波群非常宽大（280ms），这是由于氟卡尼过量，且由于父母之间沟通不畅，导致错误给药，婴儿也接受了一剂药物。氟卡尼血清水平为 1.2μg/ml，确诊为意外药物中毒。患者开始持续补液，并密切监测。3 小时后，观察到 QRS 波群明显变窄（150ms），随后在接下来的 24 小时内，QRS 波几乎完全正常化。
