Syrian Private University (SPU), Faculty of Pharmacy, Department of Biochemistry and Microbiology, Daraa international highway, Syria.
J Infect Dev Ctries. 2021 Mar 7;15(2):179-184. doi: 10.3855/jidc.13807.
The rapid emergence of bacterial resistance worldwide is a serious problem, leading to many therapeutic failures and rendering inactive effective antibiotics currently used . This problem has recently been accelerated by conflicts and its related migration. The antibiotic resistance phenomenon is diffused in Syria with a high rate of multi drug resistance cases in gram negative and gram positive organisms during and after the Syrian crisis as a result of misprescribing and overprescribing of antibiotics. The inappropriate use of antibiotic plays an important role in resistance generation. Hence, big efforts are urgently needed by using phenotypic and genetic analysis of bacterial strains against antibiotics to increase characterization and identification of mutant resistant strains and find new strategies to control the spread of antimicrobial resistance infections. This review highlights the antibacterial resistance problem in Syria, showing its negative impact and presenting a sum of efforts that are urgently needed to overcome this problem.
细菌耐药性在全球范围内迅速出现是一个严重的问题,导致许多治疗失败,并使目前使用的有效抗生素失效。最近,由于冲突及其相关的移民,这个问题加速了。在叙利亚,抗生素耐药性现象很普遍,在叙利亚危机期间和之后,革兰氏阴性和革兰氏阳性菌的多药耐药病例率很高,这是由于抗生素的不适当使用和过度使用。抗生素的不适当使用对抗菌药物耐药性的产生起着重要作用。因此,迫切需要通过对抗生素的细菌菌株进行表型和遗传分析,增加对抗突变耐药菌株的特征描述和鉴定,并寻找新的策略来控制抗菌药物耐药性感染的传播。这篇综述强调了叙利亚的抗菌药物耐药性问题,显示了其负面影响,并提出了克服这一问题所需的一系列紧急措施。