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巴西监狱中结核分枝杆菌和 HIV 合并感染的决定因素。

Determinants of coinfection tuberculosis and HIV in prisons in Brazil.

机构信息

Ribeirão Preto College of Nursing, University of São Paulo, Ribeirão Preto, Brazil.

Department of Nursing, Federal University of Paraíba, João Pessoa, Brazil.

出版信息

J Infect Dev Ctries. 2021 Mar 7;15(2):263-269. doi: 10.3855/jidc.13375.

DOI:10.3855/jidc.13375
PMID:33690210
Abstract

INTRODUCTION

Prisons context has the potential for the spread of infectious diseases, like HIV and tuberculosis, which prevalence is higher in the people deprived of liberty compared to the general population.

OBJECTIVE

to analyze which are the determinants of coinfection tuberculosis and HIV in prisons.

METHODOLOGY

Case-control study conducted in the state of São Paulo, Brazil. New cases of tuberculosis in the population deprived of liberty in the period between 2015 and 2017 were considered. Data were obtained through the notification and monitoring system for tuberculosis cases in the state of São Paulo and included sociodemographic and clinical variables and diagnosis and treatment information. The data were analyzed through frequency distribution and bivariate analysis, testing the association of the dependent variable (tuberculosis/HIV coinfection vs. tuberculosis/HIV non-coinfection) with independent variables (sociodemographic, clinical and diagnostics variables) by calculating the odds ratio and p-value.

RESULTS

Among the determinants of tuberculosis/HIV coinfection in prisons, we identified: age between 26-35, 36-55 and 56-84 years, notification in hospitals, negative sputum smear microscopy and culture, X-ray suggestive of another pathology, extrapulmonary and mixed clinical form, and alcoholism. A high percentage of death was also identified among coinfected people.

CONCLUSIONS

identifying the determinants of the tuberculosis/HIV coinfected individual can assist in the development and implementation of guidelines aimed at controlling both infections in the prison environment.

摘要

简介

监狱环境具有传播传染病的潜力,如艾滋病毒和结核病,其患病率在被剥夺自由的人群中高于普通人群。

目的

分析监狱中结核和艾滋病毒合并感染的决定因素。

方法

在巴西圣保罗州进行的病例对照研究。考虑了 2015 年至 2017 年期间被剥夺自由人群中新发的结核病病例。数据通过圣保罗州结核病病例报告和监测系统获得,包括社会人口学和临床变量以及诊断和治疗信息。通过频率分布和双变量分析对数据进行分析,通过计算比值比和 p 值,检验因变量(结核/艾滋病毒合并感染与结核/艾滋病毒非合并感染)与独立变量(社会人口学、临床和诊断变量)之间的相关性。

结果

在监狱中结核/艾滋病毒合并感染的决定因素中,我们确定了以下因素:年龄在 26-35、36-55 和 56-84 岁之间,在医院报告,痰涂片显微镜检查和培养阴性,X 射线提示另一种病理学,肺外和混合临床形式,以及酗酒。合并感染的人中有很高的死亡率。

结论

确定结核/艾滋病毒合并感染个体的决定因素有助于制定和实施旨在控制监狱环境中这两种感染的指南。

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