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新生儿压力与非压力瞬态诱发耳声发射的差异。

Differences between Pressurized and Non-Pressurized Transient-Evoked Otoacoustic Emissions in Neonatal Subjects.

机构信息

Department of Theoretical and Applied Sciences Applied Physics, eCampus University, Novedrate, Italy.

World Hearing Center, Warsaw, Poland.

出版信息

Audiol Neurootol. 2021;26(5):346-352. doi: 10.1159/000512762. Epub 2021 Mar 10.

Abstract

INTRODUCTION

Recently, Interacoustics presented a new otoacoustic emission protocol where the probe pressurizes the ear cavity, thus eliminates the risk of non-assessment (REFER outcome) due to a negative middle ear pressure. This study evaluated the characteristics and the performance of this new protocol on a newborn well-baby population.

METHODS

One hundred sixty-three newborns (age 2.7 ± 1.1 days) for a total of 294 ears were assessed randomly. Transiently evoked otoacoustic responses were acquired by the Titan device (Interacoustics), using the default and a pressurized TEOAE protocol. The data were analyzed in terms of signal to noise ratios (S/Ns) at 5 frequencies, namely, 0.87, 1.94, 2.96, 3.97, and 4.97 kHz. To assess any possible gestational age (GE) effects on the TEOAE variables, the responses were subdivided in 4 different age subgroups.

RESULTS

There were no significant differences between the left and right ear TEOAE responses, for age (in days), GE (in weeks), weight (in grams), and S/N at all 5 frequencies. Considering the pooled 294 ears, paired t tests between the default and the pressurized TEOAE data showed significant differences across all 5 frequencies (p < 0.01). The pressurized protocol generated TEOAE responses presenting larger S/Ns, and a positive additive effect of approximately 2.31 dB was observed at all tested frequencies. There were no significant GE effects on the pressurized TEOAE responses. In terms of performance, both protocols performed equally (same number of PASSes).

CONCLUSION

The pressurized TEOAE protocol generates responses with higher S/Ns which might be useful in borderline cases where the middle ear status might cause a REFER screening outcome.

摘要

简介

最近,Interacoustics 提出了一种新的耳声发射协议,该协议通过探头对耳道施压,从而消除了因中耳负压而导致无法评估(REFER 结果)的风险。本研究评估了该新协议在新生儿健康婴儿人群中的特点和性能。

方法

共有 163 名新生儿(年龄 2.7 ± 1.1 天),共 294 只耳朵,进行了随机评估。使用 Titan 设备(Interacoustics)获取瞬态诱发耳声发射反应,使用默认和加压 TEOAE 协议。根据 5 个频率(即 0.87、1.94、2.96、3.97 和 4.97 kHz)的信噪比(S/N)对数据进行分析。为了评估 TEOAE 变量是否可能受到胎龄(GE)的影响,将反应分为 4 个不同的年龄亚组。

结果

左耳和右耳的 TEOAE 反应在年龄(天)、GE(周)、体重(克)和所有 5 个频率的 S/N 方面均无显著差异。考虑到 294 只耳朵的总和,对默认和加压 TEOAE 数据进行的配对 t 检验显示在所有 5 个频率上均存在显著差异(p < 0.01)。加压协议生成的 TEOAE 反应具有更高的 S/N,在所有测试频率上观察到约 2.31 dB 的正附加效应。在加压 TEOAE 反应中,GE 无显著影响。就性能而言,两种协议的表现相同(相同数量的 PASS)。

结论

加压 TEOAE 协议产生的反应具有更高的 S/N,这可能对中耳状态可能导致 REFER 筛查结果的边界情况有用。

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