Vanderbilt Institute for Global Health, Vanderbilt University Medical Center, 2525 West End Avenue, Suite 725, Nashville, TN, 37203, United States of America.
Department of Health Policy, Vanderbilt University Medical Center, Nashville, TN, United States of America.
Health Res Policy Syst. 2021 Mar 10;19(1):32. doi: 10.1186/s12961-020-00656-z.
Antiretroviral therapy has turned HIV into a chronic condition, with morbidity from HIV-associated noncommunicable diseases (NCDs) becoming more common as HIV-infected individuals live longer. In Nigeria, the additional challenge of an under-capacitated health system highlights the need for skilled clinical investigators who can generate evidence to tackle the double burden of HIV and NCDs. The Vanderbilt-Nigeria Building Research Capacity in HIV and Non-communicable Diseases (V-BRCH) programme is a training platform to create a cohort of skilled Nigerian investigators with the capacity to lead independent clinical trial research focused on the intersection of HIV and NCDs. V-BRCH will solidify an atmosphere of continuous mentoring and skills acquisition for physician faculty at the Aminu Kano Teaching Hospital via short- and medium-term learning opportunities, paired mentoring arrangements, and mentored research projects. Trainees will attend an annual faculty enrichment programme in Nashville, in addition to on-site workshops in Nigeria on HIV-associated NCD epidemiology, clinical trials methodology, evidence synthesis, qualitative research methods, stakeholder engagement, knowledge translation, and grant writing. Research-oriented junior faculty will undergo focused training in clinical trials administration and regulatory oversight. Scholars will share best practices through mentoring panels, regular 'Works in Progress' meetings, and monthly career development seminars. Competitive seed grants will be provided to mentor-mentee teams to promote targeted in-country pilot studies focused on HIV-associated NCDs. For long-term training, physician scientists will be supported to undergo enhanced Master of Public Health (MPH) training at Bayero University in Nigeria and Master of Science in Clinical Investigation (MSCI) training at Vanderbilt. Short-term regional courses, staff development workshops, and MPH curriculum refinement will help to strengthen institutional capacity in HIV-associated NCD clinical trial research. V-BRCH will create a cohort of skilled Nigerian scientists who will be able to compete for independent funding and design and implement high quality research that will generate evidence to inform policy and practice and lead to improved outcomes for Nigerians impacted by HIV-associated NCDs.
抗逆转录病毒疗法已将 HIV 转变为一种慢性疾病，随着感染 HIV 的个体寿命延长，由与 HIV 相关的非传染性疾病（NCDs）引起的发病率变得更为常见。在尼日利亚，医疗体系能力不足的额外挑战凸显了对熟练临床研究人员的需求，这些人员能够生成证据来应对 HIV 和 NCD 的双重负担。范德比尔特-尼日利亚建设 HIV 和非传染性疾病研究能力（V-BRCH）计划是一个培训平台，旨在培养一批有能力领导专注于 HIV 和 NCD 交叉点的独立临床试验研究的尼日利亚熟练研究人员。V-BRCH 将通过短期和中期学习机会、配对指导安排和指导研究项目，为阿米努·卡诺教学医院的医师教职员工营造持续指导和技能获取的氛围。除了在尼日利亚举行的与 HIV 相关的 NCD 流行病学、临床试验方法、证据综合、定性研究方法、利益攸关方参与、知识转化和资助写作等现场研讨会外，学员还将参加纳什维尔的年度教员强化课程。以研究为导向的初级教员将接受临床试验管理和监管监督方面的重点培训。学者们将通过指导小组、定期的“工作进展”会议和每月的职业发展研讨会分享最佳实践。将向导师-学员团队提供竞争性种子赠款，以促进针对与 HIV 相关的 NCD 的国内试点研究。为了进行长期培训，将支持医师科学家在尼日利亚的贝罗大学接受强化公共卫生硕士（MPH）培训，并在范德比尔特接受临床研究硕士（MSCI）培训。短期区域课程、员工发展研讨会和 MPH 课程修订将有助于加强与 HIV 相关的 NCD 临床试验研究的机构能力。V-BRCH 将培养一批熟练的尼日利亚科学家，他们将能够竞争独立资金，并设计和实施高质量的研究，以生成证据来为政策和实践提供信息，并改善受 HIV 相关 NCD 影响的尼日利亚人的结果。
