Laboratory for Micro-Sized Functional Materials & College of Elementary Education and Department of Chemistry, Capital Normal University, Beijing 100048, China.
Beijing Key Laboratory of Construction Tailorable Advanced Functional Materials and Green Applications, School of Materials Science and Engineering, Beijing Institute of Technology, Beijing 100081, China.
J Nanosci Nanotechnol. 2021 Sep 1;21(9):4715-4725. doi: 10.1166/jnn.2021.19153.
Surface-enhanced Raman scattering (SERS) has been a sensitive tool for the accurate detection and analysis of a wide range of molecules. In the present study, a simple and repeatable approach is developed for the fabrication of a silver nanocubes/polyelectrolyte/gold film (Ag nanocubes/PE/Au film) sandwich structure as SERS substrate. An ethanol-water mixture, instead of pure water, is used as solvent to reduce the coffee ring effect by the drop coating deposition method, such that Ag nanocubes are distributed evenly on the gold film surface with polyelectrolyte as the middle layer. In 15 repeated measurements of a 10 M rhodamine 6G solution, the intensity of the Raman peak at 609 cm exhibits a relative standard deviation less than 20%. Significantly, the sandwich substrate exhibits excellent point-to-point repeatability and sample to sample reproducibility, and may be used for real-life quantitative analysis, as demonstrated by the rapid diagnosis of dual analytes of rhodamine 6G and crystal violet.
表面增强拉曼散射（SERS）已成为准确检测和分析多种分子的灵敏工具。在本研究中，开发了一种简单且可重复的方法来制备银纳米立方体/聚电解质/金膜（Ag 纳米立方体/PE/Au 膜）三明治结构作为 SERS 基底。通过滴涂沉积法，使用乙醇-水混合物代替纯水作为溶剂，可以减少咖啡环效应，使 Ag 纳米立方体均匀分布在金膜表面，其中聚电解质作为中间层。在对 10 M 若丹明 6G 溶液进行的 15 次重复测量中，在 609 cm 处的拉曼峰强度表现出小于 20%的相对标准偏差。重要的是，三明治基底表现出出色的点到点重复性和样品间重现性，并且可以用于实际的定量分析，如通过快速诊断若丹明 6G 和结晶紫的双分析物来证明。
