[Clinical features of neurogenic bladder with vesicoureteral reflux in children].

OBJECTIVE

To study the clinical features of vesicoureteral reflux (VUR) in children with neurogenic bladder (NB), and to provide a reference for its early diagnosis and treatment.

METHODS

Clinical data were collected from 26 children with NB and urinary tract infection who were admitted to the Department of Pediatric Nephrology from January 2014 to December 2019. According to the presence or absence of VUR, the children were divided into a VUR group with 11 children and a non-VUR group with 15 children. Clinical features were compared between the two groups.

RESULTS

Compared with the non-VUR group, the VUR group had a significantly higher proportion of children with non- urinary tract infection, hydronephrosis (the severity of hydronephrosis increased with the grade of VUR), abnormal Tc-DMSA renal scanning findings, elevated ratios of urinary albumin, urinary IgG and urinary transferrin to creatinine, increased residual urine volume, and increased detrusor leak point pressure ( < 0.05).

CONCLUSIONS

When NB children have the clinical manifestations of non- urinary tract infection, hydronephrosis, abnormal Tc-DMSA renal scanning findings, glomerular proteinuria, increased bladder residual urine volume, and high detrusor leak point pressure, such children may already have VUR, and so diagnosis and intervention should be performed as early as possible.