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肉眼血尿——转移性睾丸混合性生殖细胞肿瘤的一种罕见表现。

Visible haematuria-an unusual presentation of metastatic testicular mixed germ cell tumour.

作者信息

Sugrue Diarmuid Declan, Ryan James, Harris Johnathon, Cheema Ijaz

机构信息

Urology, Beaumont Hospital, Dublin, Ireland

Urology, Beaumont Hospital, Dublin, Ireland.

出版信息

BMJ Case Rep. 2021 Mar 10;14(3):e241056. doi: 10.1136/bcr-2020-241056.

DOI:10.1136/bcr-2020-241056
PMID:33692071
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7949432/
Abstract

A 29-year-old male patient presented to the emergency department with haematuria and flank pain. Ten months agopreviously, he had undergone orchidectomy and adjuvant chemotherapy for a testicular mixed germ cell tumour. Cystoscopy revealed a large bladder wall mass. The final diagnosis of yolk sac tumour was established after transurethral resection of the lesion. The patient was treated with salvage chemotherapy and placed on short-interval biochemical and radiological surveillance to assess treatment response.

摘要

一名29岁男性患者因血尿和侧腹痛就诊于急诊科。10个月前,他因睾丸混合性生殖细胞肿瘤接受了睾丸切除术和辅助化疗。膀胱镜检查发现膀胱壁有一个大肿块。经尿道切除病变组织后,最终确诊为卵黄囊瘤。该患者接受了挽救性化疗,并进行短期生化和影像学监测以评估治疗反应。

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本文引用的文献

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Improved outcomes in metastatic germ cell cancer: results from a large cohort study.转移性生殖细胞癌的改善结局:一项大型队列研究的结果。
J Cancer Res Clin Oncol. 2021 Feb;147(2):533-538. doi: 10.1007/s00432-020-03343-2. Epub 2020 Aug 9.
2
Yolk sac tumor differentiation in urothelial carcinoma of the urinary bladder: a case report and differential diagnosis.膀胱尿路上皮癌中卵黄囊瘤分化:1 例报告并鉴别诊断。
Diagn Pathol. 2020 Jun 3;15(1):68. doi: 10.1186/s13000-020-00983-3.
3
Cancer statistics, 2020.癌症统计数据,2020 年。
CA Cancer J Clin. 2020 Jan;70(1):7-30. doi: 10.3322/caac.21590. Epub 2020 Jan 8.
4
Extragonadal germ cell tumors: Not just a matter of location. A review about clinical, molecular and pathological features.性腺外生殖细胞肿瘤:不只是位置的问题。一篇关于临床、分子和病理特征的综述。
Cancer Med. 2019 Nov;8(16):6832-6840. doi: 10.1002/cam4.2195. Epub 2019 Sep 30.
5
Relapse in children with clinical stage I testicular yolk sac tumors after initial orchiectomy.临床I期睾丸卵黄囊瘤患儿初次睾丸切除术后的复发情况。
Pediatr Surg Int. 2019 Mar;35(3):383-389. doi: 10.1007/s00383-018-04426-5. Epub 2018 Dec 11.
6
The use of F-FDG PET/CT in testicular cancer.18F-氟代脱氧葡萄糖正电子发射断层显像/计算机断层扫描(F-FDG PET/CT)在睾丸癌中的应用
Transl Androl Urol. 2018 Oct;7(5):875-878. doi: 10.21037/tau.2018.09.08.
7
Conventional-Dose versus High-Dose Chemotherapy for Relapsed Germ Cell Tumors.复发性生殖细胞肿瘤的常规剂量与高剂量化疗
Adv Urol. 2018 Mar 15;2018:7272541. doi: 10.1155/2018/7272541. eCollection 2018.
8
Role of one, two and three doses of high-dose chemotherapy with autologous transplantation in the treatment of high-risk or relapsed testicular cancer: a systematic review.大剂量化疗联合自体移植治疗高危或复发睾丸癌中一剂、两剂和三剂的作用:系统评价。
Bone Marrow Transplant. 2018 Oct;53(10):1242-1254. doi: 10.1038/s41409-018-0188-3. Epub 2018 Apr 27.
9
Ongoing Clinical Trials in Testicular Cancer: The TIGER Trial.睾丸癌正在进行的临床试验:TIGER试验。
Oncol Res Treat. 2016;39(9):553-6. doi: 10.1159/000448868. Epub 2016 Sep 8.
10
The 2016 WHO Classification of Tumours of the Urinary System and Male Genital Organs-Part A: Renal, Penile, and Testicular Tumours.《2016 年世界卫生组织泌尿系统及男性生殖器官肿瘤分类—第 A 部分:肾脏、阴茎和睾丸肿瘤》。
Eur Urol. 2016 Jul;70(1):93-105. doi: 10.1016/j.eururo.2016.02.029. Epub 2016 Feb 28.