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在资源匮乏的环境下,对比研究微创眶上锁孔入路与翼点入路治疗前循环脑动脉瘤。

Comparative study between minimally invasive supraorbital craniotomy and pterional craniotomy for treating anterior circulation cerebral aneurysms in a low-resource setting.

机构信息

Department of Neurology and Neurosurgery, University Hospital, Universidade Federal do Vale do São Francisco, Petrolina, Pernambuco, Brazil.

Department of Surgery, ABC Medical School, Santo André, São Paulo, Brazil.

出版信息

Sci Rep. 2021 Mar 10;11(1):5555. doi: 10.1038/s41598-021-85115-7.

DOI:10.1038/s41598-021-85115-7
PMID:33692472
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7946868/
Abstract

The challenges encountered in performing minimally invasive approaches, such as supraorbital minicraniotomy (SOMC), in services without adequate equipment are rarely reported in the literature. This study analyzes the viability of SOMC in the treatment of cerebral aneurysms, using exactly the same resources as pterional craniotomy (PC). The results of these two techniques are compared. 35 patients underwent SOMC, compared to 50 patients underwent CP (100 aneurysms in total), using the same microsurgical instruments. The following variables were compared: operative time, angiographic cure, length of intensive care unit stay during the post-operative period, surgical complications, length of hospital stay after surgery until hospital discharge, intraoperative aneurysm rupture, aesthetic satisfaction with the scar, and neurological status at discharge. SOMC had a significantly shorter operative time in relation to PC (213.9 ± 11.09 min and 268.6 ± 15.44 min, respectively) (p = 0.0081).With respect to the cosmetic parameters assessed by the Visual Analog Scale, the average for SOMC was 94.12 ± 1.92 points, and the average for PC was 83.57 ± 4.75 points (p = 0.036). SOMC was as effective as PC in relation to successful aneurysm clipping (p = 0.77). The SOMC technique did not show advantages over PC in any other variable. Even in a general neurosurgery service lacking a specific structure for minimally invasive surgeries, SOMC was feasible and effective for treating intracranial aneurysms, using the same set of microsurgical instruments used for PC, obtaining better results in operating time and cosmetic satisfaction.

摘要

在缺乏足够设备的服务中进行微创方法(如眶上锁孔入路[SOMC])时遇到的挑战在文献中很少报道。本研究分析了使用与翼点入路(PC)完全相同的资源进行 SOMC 治疗脑动脉瘤的可行性。比较了这两种技术的结果。35 例患者接受 SOMC 治疗,50 例患者接受 CP 治疗(共 100 例动脉瘤),使用相同的显微手术器械。比较了以下变量:手术时间、血管造影治愈率、术后重症监护病房住院时间、手术并发症、术后住院至出院的住院时间、术中动脉瘤破裂、对疤痕的美容满意度和出院时的神经状态。与 PC 相比,SOMC 的手术时间明显更短(分别为 213.9±11.09 分钟和 268.6±15.44 分钟)(p=0.0081)。SOMC 的美容参数平均得分为 94.12±1.92 分,PC 的平均得分为 83.57±4.75 分(p=0.036)。SOMC 在成功夹闭动脉瘤方面与 PC 一样有效(p=0.77)。在任何其他变量方面,SOMC 技术都没有显示出优于 PC 的优势。即使在缺乏微创手术特定结构的普通神经外科服务中,SOMC 也可以使用用于 PC 的相同套显微手术器械来治疗颅内动脉瘤,在手术时间和美容满意度方面获得更好的结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1be8/7946868/3691c79a27cd/41598_2021_85115_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1be8/7946868/77505bebbe33/41598_2021_85115_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1be8/7946868/e1ea33376432/41598_2021_85115_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1be8/7946868/b4bb9337c1cd/41598_2021_85115_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1be8/7946868/3691c79a27cd/41598_2021_85115_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1be8/7946868/77505bebbe33/41598_2021_85115_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1be8/7946868/e1ea33376432/41598_2021_85115_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1be8/7946868/b4bb9337c1cd/41598_2021_85115_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1be8/7946868/3691c79a27cd/41598_2021_85115_Fig5_HTML.jpg

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本文引用的文献

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A Comparative Study between Supraorbital Keyhole and Pterional Approaches on Anterior Circulation Aneurysms.眶上锁孔入路与翼点入路治疗前循环动脉瘤的对比研究
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