Wehnert J, Kramer J, Weller J, Leike S
Klinik für Urologie, Medizinischen Akademie, Carl Gustav Carus, Dresden.
Z Urol Nephrol. 1988 Feb;81(2):73-8.
Herein we report our experience with a clinical trial of intracavernous injection of vasoactive substances (Papaverin, Dibenzyran, Regitin) in 41 patients suffering from erectile dysfunction for longer than 1 year. In 14 out of 33 patients the application of papaverin alone was already sufficient to produce an excellent erection (T/E-grade 4) under clinical conditions. The simultaneous injection of two agents (Papaverin + Dibenzyran or Papaverin + Regitin) in patients with no or insufficient response to papaverin improved the results additionally. Besides a positively effect of delay from the injection to the erection could be observed in comparison with an injection of only papaverin. In conclusion, this method combined with an autoinjection therapy is an alternative approach to treat certain patients with erectile dysfunction.
在此，我们报告了一项针对41例患有勃起功能障碍超过1年的患者进行海绵体内注射血管活性物质（罂粟碱、双苄丙胺、酚苄明）的临床试验经验。在33例患者中，有14例仅应用罂粟碱就足以在临床条件下产生极佳的勃起效果（T/E分级为4级）。对于对罂粟碱无反应或反应不足的患者，同时注射两种药物（罂粟碱 + 双苄丙胺或罂粟碱 + 酚苄明）可进一步改善结果。此外，与仅注射罂粟碱相比，可观察到从注射到勃起的延迟有积极作用。总之，这种方法与自我注射疗法相结合是治疗某些勃起功能障碍患者的一种替代方法。
