Wu Fu-Peng, Wu Xiao-Feng
Leibniz-Institut für Katalyse e.V. an der Universität Rostock, Albert-Einstein-Straße 29a, 18059, Rostock, Germany.
Dalian National Laboratory for Clean Energy, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 116023, Dalian, Liaoning, China.
Angew Chem Int Ed Engl. 2021 May 17;60(21):11730-11734. doi: 10.1002/anie.202102197. Epub 2021 Apr 16.
CuH and CuBpin are versatile catalysts and intermediates in organic chemistry. However, studies that involve both CuH and CuBpin in the same reaction is still rarely reported due to their high reactivity. Now, a study on CuH- and CuBpin-catalyzed borylative methylation of alkyl iodides with CO as the C1 source is reported. Various one carbon prolongated alkyl boranes (RCH Bpin and RCH(Bpin) ) were produced in moderate to good yields from the corresponding alkyl iodides (RI). In this cooperative system, CuH reacts with alkyl iodide faster than CuBpin.
氢化亚铜（CuH）和频哪醇硼酸铜（CuBpin）是有机化学中用途广泛的催化剂和中间体。然而，由于它们的高反应活性，在同一反应中同时涉及CuH和CuBpin的研究仍然鲜有报道。现在，有一项关于以CO作为C1源，CuH和CuBpin催化烷基碘硼氢化甲基化反应的研究被报道。由相应的烷基碘（RI）可以以中等至良好的产率制备出各种碳链延长一个碳的烷基硼烷（RCH₂Bpin和RCH(Bpin)₂）。在这个协同体系中，CuH与烷基碘的反应比CuBpin更快。
