Hata M
Dept. of Urology, School of Medicine, Keio University.
Gan To Kagaku Ryoho. 1988 May;15(5):1787-90.
One problem in the management of prostatic cancer is that about half of the patients with this disease have metastatic lesions at first diagnosis and therefore tend to be given palliative rather than radical therapy. We report here a patient with stage D prostatic cancer who was treated with a single regimen of estramustine phosphate (Estracyt). The patient was a 63-year-old man who was admitted to Keio University Hospital because of sudden onset of double vision. Under a presumptive diagnosis of brain tumor, he underwent thorough examination including brain CT, Ga and bone scan and basic blood tests, which revealed an extraordinarily high level of acid phosphatase. He was therefore referred to our urological division for investigation of possible prostatic cancer. On the basis of the results of urological examinations, a diagnosis of prostatic cancer, stage D, was confirmed. Accordingly, radical surgery was not indicated and instead he was started on oral Estracyt, to which he responded well. He has been enjoying a comfortable life to date, over one and a half years after initial referral.
前列腺癌治疗中的一个问题是,约一半的该疾病患者在初次诊断时就已有转移病灶,因此往往接受的是姑息性而非根治性治疗。我们在此报告一例患有D期前列腺癌的患者,其接受了单一疗程的磷酸雌莫司汀(癌腺治)治疗。该患者为一名63岁男性,因突然出现复视而入住庆应义塾大学医院。在初步诊断为脑肿瘤的情况下,他接受了包括脑部CT、镓扫描和骨扫描以及基础血液检查在内的全面检查,结果显示酸性磷酸酶水平异常高。因此,他被转诊至我们的泌尿外科,以调查是否可能患有前列腺癌。根据泌尿外科检查结果,确诊为D期前列腺癌。因此,不适合进行根治性手术,而是开始给他口服癌腺治,他对此反应良好。自初次转诊至今已过去一年半多,他一直过着舒适的生活。