Bauer V R, Jurcic K, Puhlmann J, Wagner H
Institut für Pharmazeutische Biologie, Universität München.
Arzneimittelforschung. 1988 Feb;38(2):276-81.
Ethanolic extracts of Echinacea purpurea, E. pallida and E. angustifolia roots were examined for immunological activity in the carbon clearance test with mice and in the granulocyte test. In the in vivo experiment all extracts, administered orally, were found to enhance phagocytosis significantly. These results correlate with the stimulation of phagocytosis in the in vitro granulocyte test. The lipophilic fractions of the extracts appeared to be more active than the polar fractions. All extracts were analyzed by HPLC in order to correlate the chemical constituents with the immunological activities.
对紫锥菊、淡紫锥菊和狭叶紫锥菊根的乙醇提取物进行了小鼠碳清除试验和粒细胞试验，以检测其免疫活性。在体内实验中，发现所有经口服给药的提取物均能显著增强吞噬作用。这些结果与体外粒细胞试验中吞噬作用的刺激结果相关。提取物的亲脂性部分似乎比极性部分更具活性。为了将化学成分与免疫活性相关联，对所有提取物进行了高效液相色谱分析。
