Takaki M, Nakayama S
Department of Physiology, Okayama University Medical School, Japan.
Brain Res. 1988 Mar 1;442(2):351-3. doi: 10.1016/0006-8993(88)91524-7.
Effects of mesenteric nerve stimulation on the electrical activity of 28 myenteric neurons were investigated in the myenteric flaps innervated with mesenteric nerves. Mesenteric nerve stimulation evoked slow excitatory postsynaptic potentials (EPSPs), whose amplitude and duration were 24.5 +/- 5.5 mV and 374.6 +/- 58.9 s in 7 AH/Type 2 neurons, respectively. Such slow EPSPs mimic the slow depolarizing action induced by exogenous substance P. It is, therefore, likely that slow EPSPs might be in part mediated by the release of substance P.
在由肠系膜神经支配的肠肌层片上，研究了肠系膜神经刺激对28个肠肌层神经元电活动的影响。肠系膜神经刺激诱发了缓慢兴奋性突触后电位（EPSP），在7个AH/2型神经元中，其幅度和持续时间分别为24.5±5.5 mV和374.6±58.9 s。这种缓慢的EPSP模仿了外源性P物质诱导的缓慢去极化作用。因此，缓慢的EPSP可能部分是由P物质的释放介导的。
