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床虱与过敏反应的关联。

Association between bed bugs and allergic reactions.

机构信息

Department of Emergency Medicine, Mayo Clinic, Jacksonville, FL, USA.

出版信息

Parasite Immunol. 2021 Jul;43(7):e12832. doi: 10.1111/pim.12832. Epub 2021 Mar 25.

DOI:10.1111/pim.12832
PMID:33704797
Abstract

AIMS

To evaluate whether bed bugs are associated with allergic reactions in patients seen in the emergency department (ED).

METHODS AND RESULTS

This retrospective study included data from 9 EDs in Ohio between February 2011 and February 2017. The study comprised 332 patients with bed bug infestation matched 1:15 with 4952 control patients without bed bugs on the basis of age, sex and the presenting ED. Compared with uninfested patients, patients infested with bed bugs were more likely to have an ED or inpatient diagnosis of pruritus, hives or urticaria (odds ratio [OR], 9.12 [95% CI, 3.41-24.42]) and to be treated in the ED with an antihistamine (OR, 3.20 [95% CI, 1.87-5.50]) or albuterol (OR, 1.59 [95% CI, 1.07-2.36]) (P ≤ .02 for all). There were no significant differences in the rates of anaphylaxis and angioedema diagnosed in patients with and without bed bugs, which occurred in <1% in both groups.

CONCLUSION

Bed bug-infested patients are more likely to be diagnosed and treated for itchy cutaneous rashes, but are not clearly associated with more severe allergic reactions.

摘要

目的

评估在急诊部就诊的患者中,床虱是否与过敏反应有关。

方法和结果

这项回顾性研究纳入了 2011 年 2 月至 2017 年 2 月期间俄亥俄州的 9 家急诊部的数据。该研究共纳入了 332 例患有床虱感染的患者,按照年龄、性别和就诊的急诊部,以 1:15 的比例与 4952 例无床虱的对照患者进行匹配。与未感染的患者相比,感染床虱的患者更有可能被诊断为瘙痒、荨麻疹或荨麻疹(优势比 [OR],9.12 [95%可信区间,3.41-24.42]),更有可能在急诊部接受抗组胺药(OR,3.20 [95%可信区间,1.87-5.50])或沙丁胺醇(OR,1.59 [95%可信区间,1.07-2.36])治疗(所有 P 值均 ≤.02)。感染床虱和未感染床虱的患者中,诊断为过敏反应和血管性水肿的发生率无显著差异,两组中均<1%。

结论

感染床虱的患者更有可能被诊断为瘙痒性皮疹,并接受治疗,但与更严重的过敏反应并无明显关联。

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