Strasberg B, Caspi A, Kusniec J, Lewin R F, Sclarovsky S, Agmon J
Electrophysiology Unit, Massada Center for Heart Diseases, Beilinson Medical Center, Petah Tikva, Israel.
Cardiology. 1988;75(2):149-53. doi: 10.1159/000174362.
A patient with clinically silent mitral valve prolapse experienced an episode of out-of-hospital cardiac arrest due to ventricular fibrillation. This arrhythmia was easily replicated in the electrophysiology laboratory and despite treatment with amiodarone alone and amiodarone in combination with propranolol. Amiodarone in combination with quinidine prevented the induction of ventricular fibrillation and proved effective during a 3-year follow-up period. Even though a clear-cut relationship between the arrhythmias and mitral valve prolapse cannot be established, this case suggests that sudden death can occur in patients with mitral valve prolapse but without the known risk factors for the development of sudden death.
一名患有临床无症状二尖瓣脱垂的患者因室颤发生了院外心脏骤停。这种心律失常在电生理实验室中很容易重现，尽管单独使用胺碘酮以及胺碘酮与普萘洛尔联合治疗。胺碘酮与奎尼丁联合使用可预防室颤的诱发，并在3年的随访期内证明有效。尽管心律失常与二尖瓣脱垂之间的明确关系尚未确立，但该病例表明，二尖瓣脱垂患者可能发生猝死，且无已知的猝死危险因素。
