脂肪酸对蛋白激酶C的激活作用及其对钙离子和磷脂的依赖性。
Activation of protein kinase C by fatty acids and its dependency on Ca2+ and phospholipid.
作者信息
Morimoto Y M, Nobori K, Edashige K, Yamamoto M, Kobayashi S, Utsumi K
机构信息
Department of Medical Biology, Kochi Medical School, Japan.
出版信息
Cell Struct Funct. 1988 Feb;13(1):45-9. doi: 10.1247/csf.13.45.
PMID:3370684
Abstract
Ca2+- and phospholipid-dependent protein kinase (PKC) was activated by arachidonic and myristic acids. This activation by both fatty acids required the calcium ion. Acidic phospholipid was also required for the activation by myristic acid, while that by arachidonic acid was inhibited by phospholipid.
摘要
钙离子和磷脂依赖性蛋白激酶（PKC）可被花生四烯酸和肉豆蔻酸激活。这两种脂肪酸的激活作用都需要钙离子。肉豆蔻酸激活还需要酸性磷脂，而花生四烯酸的激活则受到磷脂的抑制。
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