Department of Surgery and Urology for Children and Adolescents, Medical University of Gdansk, Marii Skłodowskiej-Curie 3a, Gdańsk 80-210, Poland.
Division of Pediatric Surgery, Michael E. DeBakey Department of Surgery, Texas Children's Surgical Oncology Program, Texas Children's Liver Tumor Program, Dan L. Duncan Cancer Center, Baylor College of Medicine, 7200 Cambridge Street, 7th Floor, Houston, TX 77030, USA; School of Medicine, Royal College of Surgeons in Ireland, 123 St Stephens Green, Saint Peter's, Dublin D02 YN77, Ireland.
Surg Oncol Clin N Am. 2021 Apr;30(2):219-233. doi: 10.1016/j.soc.2020.11.001.
Gastrointestinal stromal tumors and neuroendocrine tumors in adult and pediatric populations differ immensely. Despite these established differences, the extreme rarity of gastrointestinal stromal tumors and neuroendocrine tumors in the pediatric population has resulted in the lack of consensus management guidelines, making optimal surgical approaches unclear. Comprehensive management principles to guide surgical approaches in adult literature are extensive. However, these are still lacking for pediatric patients. International cooperation to develop standardized pediatric-specific guidelines is urgently warranted in the future. This article highlights the vast differences between adult and pediatric parameters and provides recommendations on optimal and novel surgical approaches in children.
成人和儿科人群中的胃肠道间质瘤和神经内分泌肿瘤差异巨大。尽管存在这些已确立的差异，但儿科人群中胃肠道间质瘤和神经内分泌肿瘤的极度罕见导致缺乏共识的管理指南，使得最佳手术方法不明确。指导成人文献中手术方法的综合管理原则非常广泛。然而，这些原则在儿科患者中仍然缺乏。未来迫切需要开展国际合作，制定标准化的儿科专用指南。本文重点介绍了成人和儿科参数之间的巨大差异，并就儿童的最佳和新型手术方法提出了建议。
