Centre of Biological Engineering, LIBRO - Laboratory of Research in Biofilms Rosário Oliveira, University of Minho, Campus de Gualtar, 4710-057, Braga, Portugal.
Institut für Medizinische Mikrobiologie, Virologie und Hygiene, Universitätsklinikum Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.
Trends Microbiol. 2021 Sep;29(9):772-775. doi: 10.1016/j.tim.2021.02.009. Epub 2021 Mar 8.
A possible association between iron and biofilm formation has been explored for a long time. Here, we focus on major recent advances that shed light on the mechanisms behind this relationship and discuss how siderophore-mediated iron acquisition may impact the virulence of important nosocomial pathogens.
铁与生物膜形成之间的可能关联已经被研究了很长时间。在这里,我们重点介绍最近的重要进展,这些进展揭示了这种关系背后的机制,并讨论了铁载体介导的铁摄取如何影响重要医院病原体的毒力。