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回到未来:癌症免疫治疗使用检查点抑制剂后多肌痛和多肌痛样综合征的识别与分类

Back to the future: identification and classification of polymyalgia rheumatica and polymyalgia rheumatica-like syndromes following cancer immunotherapy with checkpoint inhibitors.

作者信息

Manzo Ciro, Isetta Marco

机构信息

Azienda Sanitaria Locale Napoli 3 sud, Internal and Geriatric Medicine Department, Rheumatologic Outpatient Clinic Hospital "Mariano Lauro", Sant'Agnello, Italy.

Library and Knowledge Services, Central and North West London NHS Foundation Trust, London, United Kingdom.

出版信息

Reumatologia. 2021;59(1):62-63. doi: 10.5114/reum.2021.102600. Epub 2021 Feb 28.

DOI:10.5114/reum.2021.102600
PMID:33707798
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7944960/
Abstract

Polymyalgia rheumatica (PMR) and PMR-like syndromes are among the most frequent rheumatologic immuno-related adverse events (IRAEs) induced by cancer immunotherapy with "checkpoint inhibitors" (ICIs). Our short communication addresses two key methodological issues laid bare by published literature : 1) how to diagnose PMR and PMR-like syndromes following ICI therapy, 2) how PMR/PMR-like syndromes following ICI therapy are described as adverse drug reactions (ADRs).

摘要

风湿性多肌痛(PMR)和类PMR综合征是癌症免疫疗法使用“检查点抑制剂”(ICI)引发的最常见的风湿性免疫相关不良事件(IRAEs)。我们的简短通讯探讨了已发表文献中暴露的两个关键方法学问题:1)ICI治疗后如何诊断PMR和类PMR综合征,2)ICI治疗后的PMR/类PMR综合征如何被描述为药物不良反应(ADR)。

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引用本文的文献

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Are There Definite Disease Subsets in Polymyalgia Rheumatica? Suggestions from a Narrative Review.风湿性多肌痛是否存在明确的疾病亚组?一项叙述性综述的建议
Healthcare (Basel). 2025 May 23;13(11):1226. doi: 10.3390/healthcare13111226.

本文引用的文献

1
Identification and Classification of Polymyalgia Rheumatica (PMR) and PMR-Like Syndromes Following Immune Checkpoint Inhibitors (ICIs) Therapy: Discussion Points and Grey Areas Emerging from a Systematic Review of Published Literature.免疫检查点抑制剂(ICI)治疗后风湿性多肌痛(PMR)及类PMR综合征的识别与分类:基于已发表文献系统评价所产生的讨论要点及灰色地带
Medicines (Basel). 2020 Nov 3;7(11):68. doi: 10.3390/medicines7110068.
2
EULAR points to consider for the diagnosis and management of rheumatic immune-related adverse events due to cancer immunotherapy with checkpoint inhibitors.EULAR 针对癌症免疫治疗中使用检查点抑制剂引起的风湿免疫相关不良事件的诊断和管理的考虑要点。
Ann Rheum Dis. 2021 Jan;80(1):36-48. doi: 10.1136/annrheumdis-2020-217139. Epub 2020 Apr 23.
3
Polymyalgia rheumatica-like syndrome from checkpoint inhibitor therapy: case series and systematic review of the literature.免疫检查点抑制剂治疗相关肌痛性皮肌炎样综合征:病例系列及文献系统综述。
RMD Open. 2019 Apr 25;5(1):e000906. doi: 10.1136/rmdopen-2019-000906. eCollection 2019.
4
The real evidence for polymyalgia rheumatica as a paraneoplastic syndrome.风湿性多肌痛作为副肿瘤综合征的真实证据。
Reumatismo. 2018 Mar 27;70(1):23-34. doi: 10.4081/reumatismo.2018.1031.
5
Immune-Related Adverse Events Associated with Immune Checkpoint Blockade.与免疫检查点阻断相关的免疫相关不良事件。
N Engl J Med. 2018 Jan 11;378(2):158-168. doi: 10.1056/NEJMra1703481.
6
[Polymyalgia rheumatica: diagnostic and therapeutic issues of an apparently straightforward disease.].[风湿性多肌痛:一种看似简单的疾病的诊断和治疗问题。]
Recenti Prog Med. 2017 May;108(5):221-231. doi: 10.1701/2695.27559.
7
Polymyalgia rheumatica and cancer risk: the importance of the diagnostic set.风湿性多肌痛与癌症风险:诊断集的重要性。
Open Access Rheumatol. 2016 Oct 17;8:93-95. doi: 10.2147/OARRR.S116036. eCollection 2016.
8
2012 Provisional classification criteria for polymyalgia rheumatica: a European League Against Rheumatism/American College of Rheumatology collaborative initiative.2012年风湿性多肌痛临时分类标准:欧洲抗风湿病联盟/美国风湿病学会合作倡议
Arthritis Rheum. 2012 Apr;64(4):943-54. doi: 10.1002/art.34356.
9
A comparison of the sensitivity of diagnostic criteria for polymyalgia rheumatica.风湿性多肌痛诊断标准的敏感性比较
Ann Rheum Dis. 2005 Apr;64(4):626-9. doi: 10.1136/ard.2004.025296.
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A method for estimating the probability of adverse drug reactions.一种估算药物不良反应概率的方法。
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