Manzo Ciro, Isetta Marco
Azienda Sanitaria Locale Napoli 3 sud, Internal and Geriatric Medicine Department, Rheumatologic Outpatient Clinic Hospital "Mariano Lauro", Sant'Agnello, Italy.
Library and Knowledge Services, Central and North West London NHS Foundation Trust, London, United Kingdom.
Reumatologia. 2021;59(1):62-63. doi: 10.5114/reum.2021.102600. Epub 2021 Feb 28.
Polymyalgia rheumatica (PMR) and PMR-like syndromes are among the most frequent rheumatologic immuno-related adverse events (IRAEs) induced by cancer immunotherapy with "checkpoint inhibitors" (ICIs). Our short communication addresses two key methodological issues laid bare by published literature : 1) how to diagnose PMR and PMR-like syndromes following ICI therapy, 2) how PMR/PMR-like syndromes following ICI therapy are described as adverse drug reactions (ADRs).
风湿性多肌痛(PMR)和类PMR综合征是癌症免疫疗法使用“检查点抑制剂”(ICI)引发的最常见的风湿性免疫相关不良事件(IRAEs)。我们的简短通讯探讨了已发表文献中暴露的两个关键方法学问题:1)ICI治疗后如何诊断PMR和类PMR综合征,2)ICI治疗后的PMR/类PMR综合征如何被描述为药物不良反应(ADR)。