华法林对尿酸浓度无影响。
Lack of effect of warfarin on uric acid concentration.
作者信息
Walker F B, Becker D M, Kowal-Neeley B, Krongaard L S
机构信息
Department of Internal Medicine, University of Virginia School of Medicine, Charlottesville.
出版信息
Clin Chem. 1988 May;34(5):952-4.
Uric acid concentrations reportedly are increased in patients being treated with warfarin. We measured uric acid in 40 patients before and during warfarin administration. The mean pre- and post-warfarin uric acid concentrations for our patients were 0.39 mmol/L and 0.40 mmol/L, respectively, not a significant difference. Further observations of hyperuricemic patients started on warfarin are needed to prove that their risk of gout is not increased.
据报道，接受华法林治疗的患者尿酸浓度会升高。我们对40例患者在服用华法林之前和期间的尿酸水平进行了测量。我们这些患者服用华法林前后的尿酸平均浓度分别为0.39毫摩尔/升和0.40毫摩尔/升，差异不显著。需要对华法林治疗的高尿酸血症患者进行进一步观察，以证实他们患痛风的风险没有增加。
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