[大剂量VM26（4-去甲基-表鬼臼毒素-β-D-噻吨亚甲基葡糖苷）的毒性。对晚期卵巢癌治疗的贡献（作者译）]
[The toxicity of massive dosis of VM26 (4-demethyl-epipodophyllotoxin-beta-D-thenylidene glucoside). A contribution to the therapy of advanced ovarian cancer (author's transl)].
作者信息
Jankowski R P, Vahrson H
出版信息
Med Klin. 1977 Dec 9;72(49):2122-6.
PMID:337083
Abstract
19 patients with advanced ovarian cancer (FIGO-stages IIb-IV) were treated by ultra-high doses of VM26 partly according to positive oncobiograms during Multiple-drug-stoss-therapy. The toxic reactions and the cytostatic effect were investigated. The range of 57,9% remissions and the moderate toxicity suggest a specific application of VM26 in advanced ovarian cancer.
摘要
19例晚期卵巢癌（国际妇产科联盟分期IIb-IV期）患者在多药冲击疗法期间，部分根据阳性肿瘤生物学图谱接受了超高剂量的威猛（VM26）治疗。对毒性反应和细胞抑制作用进行了研究。57.9%的缓解率范围和中度毒性表明威猛（VM26）在晚期卵巢癌中有特定的应用价值。
Zotero 插件