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内镜经皮质经脑室治疗囊性颅咽管瘤:三级医疗中心32例患者的疗效分析

Endoscopic Transcortical Transventricular Management of Cystic Craniopharyngioma: Outcome Analysis of 32 Cases at a Tertiary Care Center.

作者信息

Jaiswal Somil, Jaiswal Manish, Jaiswal Pooja, Bajaj Ankur, Srivastava Chhitij, Chandra Anil, Ojha Bal Krishna, Vikas Janu, Yadav Awadhesh

机构信息

Department of Neurosurgery, King George's Medical University, Lucknow, Uttar Pradesh, India.

Department of Pathology, Integral Institute of Medical Sciences and Research, Lucknow, Uttar Pradesh, India.

出版信息

Asian J Neurosurg. 2020 Dec 21;15(4):846-855. doi: 10.4103/ajns.AJNS_252_20. eCollection 2020 Oct-Dec.

Abstract

BACKGROUND

Microsurgical resection has been considered the gold standard treatment of craniopharyngioma, but lately, it has found less favor due to its morbidity and is being replaced by minimally invasive cyst drainage procedures. We present our experience of transventricular endoscopy and cyst drainage along with its technique and have analyzed its results.

MATERIALS AND METHODS

Clinical and radiological data of all cystic craniopharyngioma patients treated by transventricular endoscopic cyst drainage and Ommaya placement were retrieved and analyzed.

RESULTS

Thirty-two patients underwent endoscopic cyst drainage during the study period. All patients had immediate clinical and radiological improvement. No significant complications were seen. All patients underwent adjuvant radiotherapy and six patients (18.7%) showed recurrence. Three patients died in the follow-up period.

CONCLUSIONS

Endoscopic transcortical transventricular cyst drainage with Ommaya reservoir along with adjuvant radiotherapy is a simple, safe, and effective treatment modality.

摘要

背景

显微手术切除一直被视为颅咽管瘤的金标准治疗方法,但近来,由于其并发症发生率,它已不太受青睐,正被微创囊肿引流手术所取代。我们介绍了经脑室内镜检查和囊肿引流的经验及其技术,并分析了其结果。

材料与方法

检索并分析了所有经脑室内镜囊肿引流和置入Ommaya储液器治疗的囊性颅咽管瘤患者的临床和放射学数据。

结果

在研究期间,32例患者接受了内镜囊肿引流。所有患者的临床和放射学症状均立即得到改善。未观察到明显并发症。所有患者均接受了辅助放疗,6例患者(18.7%)出现复发。3例患者在随访期间死亡。

结论

内镜经皮质经脑室囊肿引流联合Ommaya储液器及辅助放疗是一种简单、安全且有效的治疗方式。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/606c/7869278/6f30da0b5e2f/AJNS-15-846-g001.jpg

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