Department of Biomedical Engineering, Faculty of Engineering & DESAM Institute, Near East University, Nicosia, Turkish Republic of Northern Cyprus 99138, Turkey.
Department of Radiology, Brain Health Imaging Institute, Weill Cornell Medicine, New York, NY 10065, USA.
J Comp Eff Res. 2021 Apr;10(5):423-437. doi: 10.2217/cer-2020-0162. Epub 2021 Mar 12.
Autism spectrum disorder is a class of neurological disorders that affect the development of brain functions. This study aims to evaluate, compare and rank the therapy techniques used in the management of autism spectrum disorder using multicriteria decision-making approaches. Fuzzy PROMETHEE and fuzzy TOPSIS approaches were used. Fuzzy PROMETHEE utilizes a pair-wise comparison of alternatives under the fuzzy environment while fuzzy TOPSIS utilizes geometric distance from the positive ideal solution under the fuzzy environment for the evaluation of the effectiveness of the alternatives.The techniques selected for evaluation are applied behavioral analysis, cognitive behavioral therapy, speech therapy and pharmacological therapy such as Risperidone and Aripiprazole. Criteria used in this study include efficacy, cost and side effects, and their weights are assigned based on specific patient conditions. The results indicate that applied behavioral analysis, cognitive behavioral therapy and speech therapy are the most preferred techniques, followed by Aripiprazole and Risperidone. More criteria could be considered and the weights could be assigned according to the patient profile.
自闭症谱系障碍是一类影响大脑功能发育的神经发育障碍。本研究旨在使用多准则决策方法评估、比较和排序自闭症谱系障碍管理中使用的治疗技术。使用了模糊 PROMETHEE 和模糊 TOPSIS 方法。模糊 PROMETHEE 在模糊环境下利用对各方案的两两比较,而模糊 TOPSIS 在模糊环境下利用与正理想解的几何距离来评估各方案的有效性。选择用于评估的技术包括应用行为分析、认知行为疗法、言语疗法和药物治疗,如利培酮和阿立哌唑。本研究使用的标准包括疗效、成本和副作用,其权重根据特定患者的病情分配。结果表明,应用行为分析、认知行为疗法和言语疗法是最受欢迎的技术,其次是阿立哌唑和利培酮。可以考虑更多的标准,并根据患者的情况分配权重。