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Effects of K salt or a potassium blocker on gossypol-related hypokalemia.

作者信息

Liu G Z, Ch'iu-Hinton K, Cao J A, Zhu C X, Li B Y

机构信息

Peking Union Medical College Hospital, Beijing, China.

出版信息

Contraception. 1988 Feb;37(2):111-7. doi: 10.1016/0010-7824(88)90121-7.

DOI:10.1016/0010-7824(88)90121-7
PMID:3370986
Abstract

Gossypol was found to be an effective male contraceptive. The most serious side effect of gossypol contraception was the presumed lowering of serum potassium levels. The purpose of this present randomized and controlled study was to evaluate the merit of ingesting K salt or a potassium blocker while using gossypol. Results indicated that supplementation of K salt does not cause a reversal of the effect of gossypol on serum potassium levels and the blocker triamterene does not prevent loss of serum potassium.

摘要

相似文献

1
Effects of K salt or a potassium blocker on gossypol-related hypokalemia.
Contraception. 1988 Feb;37(2):111-7. doi: 10.1016/0010-7824(88)90121-7.
2
Clinical trial of gossypol as a male contraceptive drug. Part II. Hypokalemia study.
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1
An overview of the clinical pharmacology and therapeutic potential of gossypol as a male contraceptive agent and in gynaecological disease.
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