Department of Cardiology, Dr. Ersin Arslan Training and Research Hospital, Gaziantep, Turkey.
Department of Cardiology, Gülhane Training and Research Hospital, Ankara, Turkey.
Turk Kardiyol Dern Ars. 2021 Mar;49(2):108-119. doi: 10.5543/tkda.2021.99978.
Iatrogenic aortic dissection (IAD) during coronary interventions is a rare but fatal complication. There is not enough experience and trial on this subject. In this study, we report our IAD cases and their acute, short-term, and long-term results.
In this study, we screened 6,096 coronary angiographies performed in our center between February 2016 and February 2019. Ascending aortic dissection developed in 8 patients. A total of 7 patients had computed tomographic angiography images after the event and during the follow-up. We performed 1-month and 1-year follow-up examinations.
The incidence of IAD was 0.13%. The female sex ratio was as 63%. A total of 37% of the patients had presented with acute coronary syndrome. In 37% of the patients, dissection occured while support catheter use, but in the remaining patients, dissections developed owing to hydraulic pressure. Regardless of the Dunning staging, 7 patients were followed-up with medical treatment, and 1 patient with decreased coronary flow was referred to emergency coronary bypass surgery. Regression was in the first tomography in 4 patients and observed in the control tomography in the remaining patients with medical treatment. The in-hospital 1-month and 1-year mortality rates were 0%.
IAD is a fatal disease, and conservative follow-up is suggested due to lack of clear management recommendations. The findings in our study showed that medical treatment is the first choice for the hemodynamically stable patients when dissection is sealed by stenting; however, surgical treatment is required in patients with the decreased coronary flow.
冠状动脉介入治疗中的医源性主动脉夹层(IAD)是一种罕见但致命的并发症。目前对此主题的经验和试验还不够。在本研究中,我们报告了我们的 IAD 病例及其急性、短期和长期结果。
在本研究中,我们筛选了 2016 年 2 月至 2019 年 2 月期间在我们中心进行的 6096 例冠状动脉造影。8 例患者出现升主动脉夹层。共有 7 例患者在事件发生后和随访期间进行了计算机断层扫描血管造影检查。我们进行了 1 个月和 1 年的随访检查。
IAD 的发生率为 0.13%。女性性别比例为 63%。共有 37%的患者出现急性冠状动脉综合征。在 37%的患者中,夹层发生在使用支持导管时,但在其余患者中,夹层是由于液压引起的。无论 Dunning 分期如何,7 例患者均接受药物治疗,1 例因冠状动脉血流减少患者转至急诊冠状动脉旁路移植术。4 例患者在首次断层扫描时出现了回归,其余患者在接受药物治疗的控制断层扫描中观察到回归。住院期间 1 个月和 1 年的死亡率均为 0%。
IAD 是一种致命的疾病,由于缺乏明确的管理建议,建议保守随访。我们的研究结果表明,对于支架封闭的血流动力学稳定患者,药物治疗是首选;然而,对于冠状动脉血流减少的患者,需要手术治疗。