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中耳乳突腔再处理术:228 例儿童和成人病例的前瞻性系列研究。

Secondary Obliteration Surgery for Troublesome Mastoid Cavities: A Prospective Series of 228 Pediatric and Adult Cases.

机构信息

Ipswich Hospital NHS Trust, Ipswich, UK.

Southend University Hospital NHS Foundation Trust, Southend-on-Sea, UK.

出版信息

Otol Neurotol. 2021 Aug 1;42(7):e881-e886. doi: 10.1097/MAO.0000000000003114.

Abstract

OBJECTIVE

To present the results of a 15-year longitudinal study in a pediatric and adult population with secondary obliteration of troublesome mastoid cavities.

STUDY DESIGN

Prospective longitudinal study.

PATIENTS

Children (≤16 yrs) and adults who had obliteration surgery (228 ears) between 2000 and 2017.

INTERVENTIONS

Therapeutic.

SETTING

Tertiary referral center.

MAIN OUTCOME MEASURES

  1. Incidence of recurrent or residual cholesteatoma; 2) creation of a dry ear at 5 years postsurgery; 3) postoperative complications; 4) waterproof status of ear; 5) number of subsequent ear surgery required.

RESULTS

Thirty-one pediatric and 197 adult cases contributed to the study. At 5 years 11 of 98 (10.8%) had been lost to follow-up. Using Kaplan-Meier survival analysis, the residual rate after 5 years was 4.2% (95% CI: 0.3%-8.2%) and the recurrence rate was 1% (95% CI: 0.0%-3.0%). Of the 223 ears available for assessment, 209 (93.7%) achieved a dry state, 6 (2.7%) had intermittent discharge, 6 (2.7%) had flap necrosis requiring flap trimming, and 1 (0.4%) developed meatal stenosis. Using a cross-sectional analysis at 12 months of follow-up, the otorrhea risk was 19.2% and the risk of definitive waterproofing was 10.9%. There was a reoperation risk of 10% within 5 years which included second-stage ossiculoplasty.

CONCLUSIONS

Secondary mastoid obliteration is a safe and useful technique in treating the troublesome mastoid cavity in both children and adults. It is associated with a low cholesteatoma recidivism rate and high rate of a trouble-free ear in the long term.

摘要

目的

介绍一项在小儿和成人患者中进行的长达 15 年的复发性或继发性中耳乳突腔闭塞的纵向研究结果。

研究设计

前瞻性纵向研究。

患者

2000 年至 2017 年间接受复发性或继发性中耳乳突腔闭塞手术的儿童(≤16 岁)和成人患者(228 耳)。

干预措施

治疗性手术。

设置

三级转诊中心。

主要观察指标

1)复发性或残留胆脂瘤的发生率;2)术后 5 年时干耳的形成率;3)术后并发症;4)耳防水状态;5)需要进行的后续耳部手术次数。

结果

31 例小儿患者和 197 例成人患者纳入研究。98 例中有 11 例(10.8%)在 5 年后失访。采用 Kaplan-Meier 生存分析,术后 5 年的残留率为 4.2%(95%CI:0.3%-8.2%),复发率为 1%(95%CI:0.0%-3.0%)。223 例可评估的患耳中,209 例(93.7%)达到干燥状态,6 例(2.7%)间歇性有分泌物,6 例(2.7%)出现需要修剪皮瓣的皮瓣坏死,1 例(0.4%)发生耳道口狭窄。在 12 个月的随访时采用横断面分析,耳漏的风险为 19.2%,防水确定性的风险为 10.9%。5 年内再次手术的风险为 10%,包括二期听骨链成形术。

结论

继发性乳突腔闭塞是治疗小儿和成人麻烦的中耳乳突腔的一种安全且有效的技术。它与较低的胆脂瘤复发率和长期无忧的耳部较高发生率相关。

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