对于接受低强度至中强度化疗的实体瘤儿童，预防性使用复方磺胺甲噁唑不是必需的。
Prophylaxis With Trimethoprim/Sulfamethoxazole Is Not Necessary in Children With Solid Tumors Treated With Low-medium Intensity Chemotherapy.
机构信息
From the Pediatric Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy.
Department of Pediatric Onology and Hematology, IRCCS Ospedale Pediatrico Bambino Gesù, Rome, Italy.
出版信息
Pediatr Infect Dis J. 2021 Apr 1;40(4):354-355. doi: 10.1097/INF.0000000000003044.
Prophylaxis of Pneumocystis jiroveci pneumonia (PJP) with trimethoprim/sulfamethoxazole is a standard of care for children with hematologic malignancies, while its use in solid tumor patients is still debated. A retrospective study focusing on the use of PJP prophylaxis in patients with solid tumors was performed among 16 AIEOP centers: 1046/2863 patients did not receive prophylaxis and no cases of PJP were reported.
对于患有血液系统恶性肿瘤的儿童，用复方磺胺甲噁唑预防卡氏肺孢子虫肺炎（PJP）是一种标准的治疗方法，而在实体瘤患者中使用它仍存在争议。在 16 个 AIEOP 中心进行了一项针对实体瘤患者使用 PJP 预防的回顾性研究：2863 名患者中有 1046 名未接受预防，且未报告 PJP 病例。
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