Department of Surgery, Haaglanden Medical Center, The Hague, The Netherlands.
Department of Cardiothoracic Surgery, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands.
Obes Surg. 2021 May;31(5):2278-2290. doi: 10.1007/s11695-021-05314-z. Epub 2021 Mar 13.
The aim of this systematic review is to provide an overview of the literature on the effects of bariatric surgery on obesity-associated electrocardiogram (ECG) abnormalities and cardiac arrhythmias. Fourteen studies were included with a methodological quality ranging from poor to good. Majority of the studies showed a significant decrease of QT interval and related measures after bariatric surgery. Seven studies were included in the meta-analysis on effects of bariatric surgery on QTc interval and a significant decrease in QTc interval of - 33.6 ms, 95%CI [- 49.8 to - 17.4] was seen. Bariatric surgery results in significant decrease in QTc interval and P-wave dispersion, i.e., a normalization of initial pathology. The effects on atrial fibrillation are conflicting and not yet fully understood.
本系统评价的目的是提供关于减重手术对肥胖相关心电图(ECG)异常和心律失常影响的文献综述。共纳入 14 项研究,方法学质量从差到好不等。大多数研究显示减重手术后 QT 间期和相关指标显著降低。有 7 项研究纳入了减重手术对 QTc 间期影响的荟萃分析,结果显示 QTc 间期显著降低 - 33.6ms,95%CI [-49.8 至-17.4]。减重手术可显著降低 QTc 间期和 P 波离散度,即初始病理的正常化。对心房颤动的影响存在争议,尚未完全阐明。