Ferro-Luzzi A, Mobarhan S, Maiani G, Scaccini C, Sette S, Nicastro A, Ranaldi L, Polito A, Azzini E, Torre S D
National Institute of Nutrition, Rome, Italy.
Eur J Clin Nutr. 1988 Jan;42(1):5-13.
The interrelationship between habitual alcohol consumption, dietary intakes and vitamin status was examined in 393 elderly subjects (188 men, 205 women, age range 65-90 years) resident in seven retirement homes throughout Italy. Individual food intake was assessed by the 7-day precise weighing method. Fasting blood was tested for riboflavin (erythrocyte glutathione reductase activity coefficient), thiamine (erythrocyte transketolase activity), retinol (fluorimetry) and folic acid status. Alcohol contributed on average 12 per cent of total energy intake in men, and 6 per cent in women. Forty-eight per cent of males and 39 per cent of females were classified as heavy drinkers (HD) with 48 and 28 g/d average alcohol intakes respectively. There was a general tendency for women to add alcohol to their habitual diet, as revealed by the positive correlation between total energy intake and alcohol intake. The higher energy intakes of HD women were also reflected in their higher body weights. Men tended to displace food energy partially by alcohol. Dietary risk of malnutrition, high for vitamin A, and moderate to low for vitamins B1 and B2, did not increase with alcohol consumption. Biochemical evidence of malnutrition indicated a significant deterioration of folate status in HD of both sexes, and for B1 in HD males only; there was no change in riboflavin status. Plasma levels of retinol were higher, and prevalence of vitamin A deficiency lower, in HD, a finding that warrants further investigation.(ABSTRACT TRUNCATED AT 250 WORDS)
在意大利各地七家养老院居住的393名老年受试者(188名男性,205名女性,年龄在65至90岁之间)中,研究了习惯性饮酒、饮食摄入与维生素状况之间的相互关系。通过7天精确称重法评估个人食物摄入量。对空腹血液进行核黄素(红细胞谷胱甘肽还原酶活性系数)、硫胺素(红细胞转酮醇酶活性)、视黄醇(荧光法)和叶酸状况检测。男性饮酒平均占总能量摄入的12%,女性为6%。48%的男性和39%的女性被归类为重度饮酒者(HD),平均酒精摄入量分别为48克/天和28克/天。总能量摄入与酒精摄入量之间的正相关表明,女性有在习惯性饮食中添加酒精的普遍倾向。HD女性较高的能量摄入也反映在她们较高的体重上。男性倾向于部分用酒精替代食物能量。维生素A营养不良的饮食风险较高,维生素B1和B2的风险为中度至低度,不会随着酒精消费而增加。营养不良的生化证据表明,男女HD组的叶酸状况均显著恶化,仅HD男性的维生素B1状况恶化;核黄素状况没有变化。HD组的血浆视黄醇水平较高,维生素A缺乏的患病率较低,这一发现值得进一步研究。(摘要截短为250字)