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边缘性高血压大鼠:一种用于研究环境诱导性高血压机制的模型。

The borderline hypertensive rat: a model for studying the mechanisms of environmentally induced hypertension.

作者信息

Lawler J E, Cox R H, Sanders B J, Mitchell V P

机构信息

Department of Psychology, University of Tennessee, Knoxville 37996-0900.

出版信息

Health Psychol. 1988;7(2):137-47. doi: 10.1037//0278-6133.7.2.137.

Abstract

The borderline hypertensive rat (BHR) is a first-generation cross between the spontaneously hypertensive rat and the normotensive Wistar-Kyoto rat. The BHR develops frank hypertension when chronically stressed or when fed a high-sodium diet. Stress-induced hypertension can be blocked by exercise. The role of the central nervous system and kidney in hypertension development in this model is discussed.

摘要

边缘性高血压大鼠(BHR)是自发性高血压大鼠与正常血压的Wistar-Kyoto大鼠的第一代杂交种。当长期处于应激状态或喂食高钠饮食时,BHR会发展为明显的高血压。运动可以阻断应激诱导的高血压。本文讨论了该模型中中枢神经系统和肾脏在高血压发展中的作用。

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