Lawler J E, Cox R H, Sanders B J, Mitchell V P
Department of Psychology, University of Tennessee, Knoxville 37996-0900.
Health Psychol. 1988;7(2):137-47. doi: 10.1037//0278-6133.7.2.137.
The borderline hypertensive rat (BHR) is a first-generation cross between the spontaneously hypertensive rat and the normotensive Wistar-Kyoto rat. The BHR develops frank hypertension when chronically stressed or when fed a high-sodium diet. Stress-induced hypertension can be blocked by exercise. The role of the central nervous system and kidney in hypertension development in this model is discussed.
边缘性高血压大鼠(BHR)是自发性高血压大鼠与正常血压的Wistar-Kyoto大鼠的第一代杂交种。当长期处于应激状态或喂食高钠饮食时,BHR会发展为明显的高血压。运动可以阻断应激诱导的高血压。本文讨论了该模型中中枢神经系统和肾脏在高血压发展中的作用。