Taouqi Myriam, Veyri Marianne, Brégigeon Sylvie, Pibarot Michèle, Solas Caroline, Makinson Alain, Marcelin Anne-Geneviève, Choquet Sylvain, Spano Jean-Philippe, Poizot-Martin Isabelle
Réseau régional de cancérologie Oncopaca-Corse, 270, boulevard de Sainte-Marguerite, 13009 Marseille, France.
Sorbonne Université, Inserm, institut Pierre Louis d'épidémiologie et de Santé Publique (iPLESP), AP-HP, hôpital Pitié-Salpêtrière, service d'oncologie médicale, 47-83, boulevard de l'Hôpital, 75013 Paris, France.
Bull Cancer. 2021 Apr;108(4):369-376. doi: 10.1016/j.bulcan.2020.11.019. Epub 2021 Mar 10.
HIV testing is recommended at time of cancer diagnosis, HBV and HCV screening because of the risk of reactivation with certain anticancer drugs.This is a cross-sectional study. The objectives were to assess the screening practices in cancer patients and the satisfaction of professionals in the event of use of the CancerHIV network. A questionnaire drafted by the CancerHIV expert and the OncoPaca-Corse Regional Cancer Network (RCN) was distributed in the region at the end of 2018 (part 1: V1) before being extended to the national level via the CancerHIV network (part 2: V2). Participation reached 160 and 130 respondents (V1 and V2, respectively). At the initial cancer assessment, 23% of respondents declared that they systematically screened for HIV at V1 (V2: 17%), 25% for HBV (V2: 20%) and 24% for HCV (V2: 19%). Before immunotherapy, the rates were 54% for HIV in V1 (V2: 52%), 57% for HBV (V2: 60%) and 55% for HCV (V2: 57%). Among the respondents, satisfaction when requesting a regional or national remedy was high (almost 100%). Screening for HIV, HBV and HCV allows supervised prescription of immunosuppressive or cytotoxic treatment to a potentially immunosuppressed patient. This study, resulting of an original collaboration between a RCN and a national expert network, underlines the lack of screening at the 2 examined stages of patient care, and the need for raising practitioners' awareness to recommendations.
由于某些抗癌药物存在激活风险,因此建议在癌症诊断时进行HIV检测、HBV和HCV筛查。这是一项横断面研究。其目的是评估癌症患者的筛查情况以及专业人员在使用CancerHIV网络时的满意度。由CancerHIV专家和奥克西塔尼-科西嘉地区癌症网络(RCN)起草的问卷于2018年底在该地区发放(第1部分:V1),之后通过CancerHIV网络扩展至全国范围(第2部分:V2)。参与调查的分别有160名和130名受访者(V1和V2)。在初次癌症评估时,23%的受访者表示他们在V1时会系统性地筛查HIV(V2时为17%),25%筛查HBV(V2时为20%),24%筛查HCV(V2时为19%)。在免疫治疗前,V1时HIV的筛查率为54%(V2时为52%),HBV为57%(V2时为60%),HCV为55%(V2时为57%)。在受访者中,申请地区或国家补救措施时的满意度较高(近100%)。对HIV、HBV和HCV进行筛查可对潜在免疫抑制患者的免疫抑制或细胞毒性治疗进行监督处方。这项由一个RCN和一个国家专家网络开展的原创合作研究强调了在患者护理的两个检查阶段缺乏筛查,以及提高从业者对相关建议认识的必要性。