Department of Pharmaceutical Engineering, Inje University, Gimhae 50834, Republic of Korea.
Department of Pharmacy, College of Pharmacy, Inje University, Gimhae 50834, Republic of Korea.
J Nanosci Nanotechnol. 2021 Jul 1;21(7):4051-4054. doi: 10.1166/jnn.2021.19174.
The purpose of this study is to investigate the surface activity of starch nanocrystals (SNC), material derived from starch, and confirm their usefulness as a surfactant. In order to evaluate the surface activity, the surface tension change of suspended SNC solution via the Wilhelmy plate method was measured and the values were compared with various synthetic surfactants. The effect of SNC as emulsifier was evaluated on emulsion formation and physical stability. The surface tension of the SNC-dispersed solution was decreased while its concentration was increased. When the 5.0% (w/v) of SNC was added, the surface tension was decreased from 70.3 to 49.5 mN/m. It was confirmed that the physical stability of the emulsion prepared by adding the SNC was improved compared to that of surface inactivity material (PEG 400). The phase separation was observed within 1 hour after preparation of the emulsion containing PEG 400, but the emulsion containing SNC was stable for 5 hours or more. To summarize this study, SNC, a natural-derived and non-toxic material, exhibits sufficient surface activity, thereby confirming the possibility of being applied to the food and pharmaceutical industry.
本研究旨在研究淀粉纳米晶体(SNC)的表面活性,该物质源自淀粉,并确认其作为表面活性剂的用途。为了评估表面活性,通过吊片法测量了悬浮 SNC 溶液的表面张力变化,并将其与各种合成表面活性剂的值进行了比较。评估了 SNC 作为乳化剂在乳液形成和物理稳定性方面的效果。随着 SNC 浓度的增加,SNC 分散溶液的表面张力降低。当添加 5.0%(w/v)的 SNC 时,表面张力从 70.3 降低至 49.5 mN/m。与表面非活性物质(PEG 400)相比,添加 SNC 制备的乳液的物理稳定性得到了改善。含有 PEG 400 的乳液在制备后 1 小时内观察到相分离,但含有 SNC 的乳液稳定 5 小时或更长时间。总的来说,本研究表明,源自天然且无毒的 SNC 具有足够的表面活性,从而确认了其在食品和制药工业中应用的可能性。