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急性肺栓塞伴心跳骤停致气管支气管阻塞,采用体外膜肺氧合治疗。

Tracheobronchial Obstruction Due to Blood Clots in Acute Pulmonary Embolism with Cardiac Arrest Managed with Extracorporeal Membrane Oxygenation.

机构信息

Department of Cardiology, Fujieda Municipal General Hospital, Japan.

出版信息

Intern Med. 2021 Sep 1;60(17):2811-2817. doi: 10.2169/internalmedicine.6856-20. Epub 2021 Mar 15.

Abstract

A 66-year-old Japanese woman developed pulseless electrical activity following an acute pulmonary embolism and was treated with thrombolytic therapy. She remained hemodynamically unstable and therefore underwent extracorporeal membrane oxygenation (ECMO). While receiving treatment with ECMO, blood clots induced by endobronchial hemorrhage caused tracheobronchial airway obstruction, leading to ventilatory defect. Furthermore, her cardiac function improved, resulting in cerebral hypoxemia progression. Therefore, the blood clots were removed with a Fogarty balloon catheter and endobronchial urokinase administration, resulting in improvement in her respiratory condition. Finally, ECMO was decannulated, and the patient was discharged from our hospital without difficulties in her activities of daily living.

摘要

一位 66 岁的日本女性在急性肺栓塞后出现无脉性电活动,并接受了溶栓治疗。她的血流动力学仍不稳定,因此接受了体外膜氧合(ECMO)治疗。在接受 ECMO 治疗期间,支气管内出血引起的血栓导致了气管支气管气道阻塞,引起通气缺陷。此外,她的心脏功能改善,导致脑缺氧进展。因此,使用 Fogarty 球囊导管和支气管内尿激酶清除了血栓,改善了她的呼吸状况。最后,ECMO 脱机,患者出院,日常生活活动无困难。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f0a/8479226/825144144b10/1349-7235-60-2811-g001.jpg

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