Cuomo Roberto, Giardino Francesco Ruben, Neri Alessandro, Nisi Giuseppe, Brandi Cesare, Zerini Irene, Jingjian Han, Grimaldi Luca
Unit of Plastic and Reconstructive Surgery, S. Maria Alle Scotte Hospital, Department of Medicine, Surgery, and Neuroscience, University of Siena, Siena, Italy.
Unit of General and Oncological Surgery, S. Maria Alle Scotte Hospital, Department of Medicine, Surgery, and Neuroscience, University of Siena, Siena, Italy.
Breast Care (Basel). 2021 Feb;16(1):36-42. doi: 10.1159/000506347. Epub 2020 Feb 26.
Acellular dermal matrix (ADM) were introduced in the early 2000s and more recently permitted new protocols for breast reconstruction allowing a short operative time with improved outcomes until the new muscle-sparing breast reconstruction proposed in 2014 using the Braxon® ADM. The aim of this research is to propose a technique to improve the aesthetic outcome using Braxon ADM with prepectoral implants.
The enrolled patients were submitted to a nipple skin-sparing mastectomy leaving 1 additional centimeter of subcutis on the proximal part of the upper pole of the breast (see Surgical Technique). Aesthetic outcomes were compared to those obtained with traditional breast reconstruction with prosthesis and the Braxon ADM placed in the prepectoral space. Mean values of aesthetic outcomes were analyzed using the Student test, and the κ test was used to analyze interobserver variability.
The overall aesthetic score was improved of 29.6% of the patients; in particular the most improved score was that for contour (+98.01%). Statistical significance was found for contour, upper pole definition, and total score average ( < 0.05). The κ test showed interobserver variability with a good level of agreement on contour (κ = 0.832).
The proposed technique has allowed attainment of good results in terms of aesthetic outcomes. In a small sample we did not register any particular complications but we verified a better satisfaction on the evaluation of the aesthetic result (level of evidence: 3).
无细胞真皮基质(ADM)于21世纪初被引入,最近出现了用于乳房重建的新方案,可缩短手术时间并改善效果,直到2014年提出使用Braxon® ADM进行新的保留肌肉的乳房重建。本研究的目的是提出一种使用Braxon ADM和胸前植入物来改善美学效果的技术。
入组患者接受保留乳头的皮下乳房切除术,在乳房上极近端保留额外1厘米的皮下组织(见手术技术)。将美学效果与传统假体乳房重建以及将Braxon ADM置于胸前间隙的情况进行比较。使用学生t检验分析美学效果的平均值,κ检验用于分析观察者间的变异性。
29.6%的患者整体美学评分得到改善;特别是改善最明显的评分是轮廓(+98.01%)。在轮廓、上极清晰度和总分平均值方面发现有统计学意义(P<0.05)。κ检验显示观察者间在轮廓方面存在变异性,但一致性良好(κ = 0.832)。
所提出的技术在美学效果方面取得了良好的结果。在小样本中,我们未记录到任何特殊并发症,但我们证实了在美学效果评估方面有更高的满意度(证据级别:3)。