Seswandhana Rosadi, Makrufardi Firdian, Sudjatmiko Gentur
Plastic, Reconstructive, and Aesthetic Surgery Division, Department of Surgery, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito Hospital, Yogyakarta, 55281, Indonesia.
Department of Plastic Reconstructive, and Aesthetic Surgery, Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
Ann Med Surg (Lond). 2021 Feb 23;63:102183. doi: 10.1016/j.amsu.2021.102183. eCollection 2021 Mar.
Cleft lip with or without cleft palate is one of the most common birth defects and is certainly the most visible. Fistula rate after primary palatoplasty was ranging between 10 and 23% and could be detected in the first three weeks after surgery. The cleft width is the frequent factor which was assumed to correspond to fistula occurrence. This study aimed to find correlation between fistula occurrence with cleft width and palatum width ratio after primary palate repair.
A prospective cohort study was conducted on 16 subjects, which consisted of 10 males and 6 females. We measured width of cleft palate, width of rest palate and width of palate arch on three level measurements (posterior, junction and anterior). The surgery was performed using the two-flap and three layers suturing technique.
Sixteen patients were enrolled in this study during January and February 2008 . Ten patients were diagnosed with unilateral cleft palate while six patients had bilateral cleft palate. Mean of age was 22.31 ± 5.86 month. Correlation analysis between fistula occurrence and cleft width, cleft width-remnant palate width ratio and cleft width-palate arch width ratio using logistic regression did not show statistical correlation, and the same result was found between fistula occurrence and hemoglobin level, white blood count, nutritional status, cleft type and caries dentis factors ( > 0.05).
Width of the cleft is not a factor associated with fistula occurrence. Two-flap three layers technique could be considered as a simple technique and gives a low rate of fistula occurrence.
唇裂伴或不伴腭裂是最常见的出生缺陷之一，也是最明显的出生缺陷。一期腭裂修复术后的瘘管发生率在10%至23%之间，术后前三周即可检测到。腭裂宽度是被认为与瘘管发生相关的常见因素。本研究旨在探讨一期腭裂修复术后瘘管发生与腭裂宽度及腭部宽度比值之间的相关性。
对16名受试者进行了一项前瞻性队列研究，其中男性10名，女性6名。我们在三个水平测量点（后部、交界处和前部）测量了腭裂宽度、剩余腭部宽度和腭弓宽度。手术采用两瓣三层缝合技术。
2008年1月至2月期间，16例患者纳入本研究。10例患者被诊断为单侧腭裂，6例患者为双侧腭裂。平均年龄为22.31±5.86个月。使用逻辑回归分析瘘管发生与腭裂宽度、腭裂宽度-剩余腭部宽度比值和腭裂宽度-腭弓宽度比值之间的相关性，未显示出统计学相关性，瘘管发生与血红蛋白水平、白细胞计数、营养状况、腭裂类型和龋齿因素之间也得到了相同的结果（>0.05）。
腭裂宽度不是与瘘管发生相关的因素。两瓣三层技术可被认为是一种简单的技术，且瘘管发生率较低。
