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芘标记载脂蛋白A-I的数据集、模型开发及拟合以监测其无脂形式的寡聚体种类。

Dataset on pyrene-labelled apolipoprotein A-I, model development and fitting to monitor oligomeric species of its lipid-free form.

作者信息

Tárraga Wilson A, Garda Horacio A, Falomir Lockhart Lisandro J, Gonzalez Marina C

机构信息

Instituto de Investigaciones Bioquímicas de La Plata "Rodolfo Brenner" (INIBIOLP), Centro Científico Tecnológico-La Plata, Calle 60 y 120 (1900), La Plata, Argentina.

Facultad de Ciencias Médicas, Universidad Nacional de La Plata, La Plata, Argentina.

出版信息

Data Brief. 2021 Feb 13;35:106829. doi: 10.1016/j.dib.2021.106829. eCollection 2021 Apr.

Abstract

This article contains data for the self-association of pyrene-labelled single Cys-mutants of apolipoprotein A-I (apoA-I). Mathematical models were developed to characterise the self-association events at different cysteine positions on apoA-I obtained as a function of protein concentration based on the multi-parametric spectrum of pyrene, particularly -value and excimer emissions. The present work complements data related to the article entitled "Analysis of pyrene-labelled apolipoprotein A-I oligomerisation in solution: Spectra deconvolution and changes in -value and excimer formation" Tárraga et al. [1].

摘要

本文包含载脂蛋白A-I(apoA-I)的芘标记单半胱氨酸突变体自缔合的数据。基于芘的多参数光谱,特别是振动带强度值和准分子发射,建立了数学模型,以表征apoA-I上不同半胱氨酸位置的自缔合事件,这些事件是作为蛋白质浓度的函数获得的。本研究补充了与题为《溶液中芘标记的载脂蛋白A-I寡聚化分析:光谱去卷积以及振动带强度值和准分子形成的变化》的文章相关的数据,作者为塔拉加等人[1]。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c5ee/7921477/c6a0696081a4/gr1.jpg

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