Universidade Federal de São Paulo - Unifesp, São Paulo, Brazil.
Banco de Olhos de Sorocaba, Sorocaba, Brazil.
Eur J Ophthalmol. 2021 Nov;31(6):3483-3489. doi: 10.1177/11206721211000646. Epub 2021 Mar 15.
To investigate the role of ICRS in halting keratoconus progression in a large sample of patients.
A retrospective, non-comparative, interventional study based on the review of medical records of patients diagnosed with keratoconus who underwent Ferrara corneal ring segment implantation. A retrospective chart analysis study of 123 operated eyes with follow-up ranging from 3 to 16 years (mean 5.3 ± 3.6 years) was performed. This study was carried out at Ocular Surgery Unit, São Paulo, Brazil. All topographic data were obtained from Pentacam (Oculus, Arlington, USA). The same surgeon performed all surgeries, and the Ferrara ICRS nomogram was used for ICRS selection in all cases.
Corrected distance visual acuity, keratometry, and topographic astigmatism improved in most cases, with statistical significance. In 42 eyes (53.8%), there was an increase in K1 or K2, and in 36 (46.2%), there was a reduction or maintenance in K1. Considering a difference higher than 1 D, between 3-month post-surgery and final visit (group 3), 32 eyes (41%) showed an increase, and 46 eyes (59%) ended equal or below this value.
The implantation of ICRS showed improvement in visual and keratometric indexes. The majority of patients did not increase more than one diopter in keratometric values after ICRS implantation. ICRS may be effective for slowing disease progression, especially in older patients.
在大量患者中研究 ICRS 在阻止圆锥角膜进展中的作用。
这是一项回顾性、非对照、干预性研究，基于对接受 Ferrara 角膜环段植入术的圆锥角膜患者的病历回顾。对 123 只手术眼进行了回顾性图表分析研究，随访时间为 3 至 16 年（平均 5.3±3.6 年）。该研究在巴西圣保罗的眼科手术科进行。所有地形图数据均来自 Pentacam（美国 Arlington 的 Oculus）。所有手术均由同一位外科医生进行，并且在所有情况下均使用 Ferrara ICRS 图表选择 ICRS。
在大多数情况下，矫正远视力、角膜曲率和地形图散光均有改善，且具有统计学意义。在 42 只眼（53.8%）中，K1 或 K2 增加，在 36 只眼（46.2%）中，K1 减少或保持不变。考虑到术后 3 个月与最终随访（第 3 组）之间差值高于 1D，32 只眼（41%）显示增加，46 只眼（59%）则等于或低于该值。
ICRS 的植入改善了视力和角膜曲率指标。大多数患者在植入 ICRS 后角膜曲率值增加不超过 1 个屈光度。ICRS 可能对减缓疾病进展有效，特别是在老年患者中。
