Department of Chemistry, Dartmouth College, Hanover, New Hampshire 03755, USA.
Chem Soc Rev. 2021 May 7;50(9):5631-5649. doi: 10.1039/d1cs00122a. Epub 2021 Mar 15.
BF-based fluorophores, such as the well-known BODIPY (4,4-difluoro-4-bora-3a,4a-diaza-s-indacene) dye, are prevalently used in diverse research areas (e.g., bioimaging and chemosensing) as they exhibit promising features including high quantum yields, fine-tuned absorption and emission spectra as well as good photostability and biocompatibility. While BODIPY dyes are most commonly used in such applications, other BF-based fluorophores, such as BOPHY (bis(difluoroboron)-1,2-bis((1H-pyrrol-2-yl)methylene)hydrazine - which possess their own characteristic features - are rising in popularity and are being used in a range of applications spanning from molecular sensors to photosensitizers for solar cells. This review examines select examples of BOPHY dyes to highlight the progression of their development while detailing their syntheses and photophysical properties including structure-property relationships. Applications of a number of substituted BOPHYs made by the methods described in this review are also presented.
基于 B-F 的荧光团，如著名的 BODIPY（4,4-二氟-4-硼-3a,4a-二氮杂-s-茚）染料，在生物成像和化学传感等多个研究领域得到广泛应用，因为它们具有高量子产率、精细的吸收和发射光谱以及良好的光稳定性和生物相容性等有前途的特性。虽然 BODIPY 染料最常用于此类应用，但其他基于 B-F 的荧光团，如 BOPHY（双（二氟硼）-1,2-双（（1H-吡咯-2-基）亚甲基）肼-具有其自身的特征-越来越受欢迎，并在从分子传感器到太阳能电池的光敏剂的各种应用中得到了应用。本综述选择了一些 BOPHY 染料的实例，以突出其发展进程，同时详细介绍其合成和光物理性质，包括结构-性质关系。还介绍了通过本综述中所述方法合成的几种取代 BOPHY 的应用。
